Uridine-5′-diphosphoglucuronic acid trisodium cusbo CAS:63700-19-6 budo cad
| Lambarka buugaagta | XD90382 |
| Magaca Alaabta | Uridine-5'-diphosphoglucuronic acid trisodium cusbo |
| CAS | 63700-19-6 |
| Qaanuunka molecular | C15H19N2O18P2Na3 |
| Miisaanka Molecular | 646.20 |
| Faahfaahinta Kaydinta | <-4 °C |
Tilmaamaha Alaabta
| Qiimayn | 99% |
| Muuqashada | budo cad |
Daraasadda hadda jirta waxay ujeedadeedu tahay in la baaro saameynta sunta irinotecan ee biotransformation ee glucoaurantiyo-obtusin ilaa aurantio-obtusin.Maamulka intraperitoneal (ip) ee 100 mg / kg aurantio-obtusin ayaa si weyn u kordhisay sunta irinotecan, laakiin maamulka ip ee 100 mg / kg glucoaurantiyo-obtusin waxay muujisay saameyn aan fiicneyn oo ku wajahan sunta irinotecan.Intaa waxaa dheer, habka ayaa lagu sharraxay iyada oo la go'aaminayo awoodda ka-hortagga ee glucoaurantio-obtusin iyo aurantio-obtusin ee ku wajahan dheef-shiid kiimikaadka glucuronidation ee SN-38 kaas oo loo tixgeliyey inuu yahay sheyga ugu weyn ee firfircoon ee mas'uulka ka ah sunta irinotecan.Natiijooyinka waxay muujiyeen in aurantio-obtusin ay muujisay xannibaad xooggan oo tartan ah oo ku wajahan glucuronidation of SN-38, laakiin awoodda xannibaadda dayacan ee glucoaurantiyo-obtusin ee ku wajahan SN-38 glucuronidation ayaa la arkay.Natiijooyinkani waxay muujiyeen in biotransformation of glucoaurantio-obtusin xagga aurantio-obtusin ay kordhisay sunta irinotecan iyada oo loo marayo xannibaadda korodhka SN-38 glucuronidation.
