N-Acetyl -L-cysteine CAS:616-91-1 98% budada crystalline cad
| Lambarka buugaagta | XD90127 |
| Magaca Alaabta | N - Acetyl -L-cysteine |
| CAS | 616-91-1 |
| Qaanuunka molecular | C5H9NO3S |
| Miisaanka Molecular | 163.1949 |
| Faahfaahinta Kaydinta | 2 ilaa 8 °C |
| Xeerka Tarifka La Iswaafajiyay | 29309016 |
Tilmaamaha Alaabta
| Meesha dhalaalaysa | 106-112°C |
| Wareegid gaar ah | +21°-+25° |
| Biraha culus | <10ppm |
| Arsenic | <1pm |
| pH | 2.0-2.8 |
| Khasaare xagga qallajinta | ugu badnaan 1.0% |
| Sulfate | <0.03% |
| Qiimayn | 98% min |
| Birta | <20ppm |
| Hadhaaga dabka | ugu badnaan .5% |
| Amooniyam | <0.02% |
| cl | <0.04% |
| Muuqashada | Budada crystalline cad |
| Xaalada Xalka | >98% |
N-Acetyl-L-cysteine waa amino acid acetylated leh oo leh astaamaha antioxidant iyo mucolytic.Labadan hawlood waxay muujiyeen N-Acetyl-L-cysteine inay si gaar ah ugu habboon tahay daaweynta kiimikada ee cystic fibrosis, halkaas oo dabeecadda antioxidant / yaraynta dabeecadda ay hagaajiso sifada nidaamka isku-dheellitir la'aanta nidaamka CF iyo sifooyinka mucolytic ee xaruntu waxay caqabad ku tahay ciriiriga iyo bararka la xiriira xaaladdan dib-u-dhaqaajinta.Sida mucolytic, N-Acetyl-L-cysteine waxay u adeegtaa inay kala daadiso curaarta disulfide ee ku dhex jira mucoproteins, debecsan oo nadiifisa viscosity of sputum.N-Acetyl-L-cysteine wuxuu muujinayaa ficil ku habboon glutathione, labaduba waxay muujinayaan waxqabadka antioxidant iyada oo loo marayo shaqeyntooda thiol, labadaba waxaa lagu muujiyey inay ka difaacaan diiqada peroxidative ee la xiriirta shoogga septic.N-Acetyl-L-cysteine ayaa sidoo kale lagu muujiyay in ay keento apoptosis ee unugyada muruqyada siman ee xididada, taas oo muujinaysa in unugyadani ay si ka duwan uga jawaabaan isbeddelada hoos u dhaca-oxidation-ka marka loo eego unugyada kale ee sida caadiga ah loo ilaaliyo joogitaanka antioxidants.Isku xirka la yaabka leh ee unugyada muruqa siman ee xididada xididada ayaa tilmaamaya N-Acetyl-L-cysteine inay tahay faragelin rajo leh oo ku saabsan kororka arteriosclerotic ee unugyadan.
Waxyaabaha kiimikaad: N-acetyl-L-cysteine budada crystalline cad, oo leh ur u eg toonta iyo dhadhan dhanaan.Hygroscopic, ku milmay biyaha ama ethanol, aan milmin ether iyo chloroform.Waa aashito ku jirta dareeraha aqueous (pH2-2.75 ee 10g/LH2O), mp101-107℃Chemicalbook.Alaabtani waa N-acetylated devative of cysteine.Moleekulku waxa uu ka kooban yahay koox sulfhydryl ah, kaas oo jebin kara bond disulfide (-SS-) ee bond peptide mucin, oo markaas u rogi silsilad mucin galay silsilad peptide yar yar, yaraynaysaa Sababta oo ah viscosity ee mucin, alaabtani waa kala diri. daawada xaakada viscous, purulent sputum iyo xabka neefsiga.
isdhexgalka daawada:
1. In aan lagu darin penicillin, cephalosporin iyo antibiyootigyada tetracycline, maadaama kan dambe uu noqon karo mid aan waxtar lahayn.
2. Isku darka ama isticmaalka beddelka ah ee isoproterenol waxay hagaajin kartaa saameynta daaweynta waxayna yareyn kartaa falcelinta xun.
3. Iska ilaali taabashada maacuunta birta iyo caagga ah, oksaydhiyeyaasha, iyo ogsijiinta.
Isticmaalka: reagen-yaasha noolaha, alaabta ceeriin, thiol (-SH) ee moleculeku waxay jebin karaan silsiladda disulfide (-SS) ee isku xidha silsiladda mucin peptide ee xaakada xabka.Mucin wuxuu u beddelaa buugga Kiimikada silsilad yar oo peptide ah, taas oo yaraynaysa viscosity of sputum;Waxa kale oo ay jebin kartaa fiilooyinka DNA-da ee xaakada purulent, sidaa darteed kaliya ma milmi karto xaakada viscous cad laakiin sidoo kale ma diri karto xaakada purulent.
Isticmaala: Daawada, waxa loo isticmaalaa sida daawada xaakadu kala dirto.Cilmi-baarista bayoolajiga, waxa loo istcimaalaa dawo ka-hortag u ah milanka xaakada iyo sumowga acetaminophen ee daawada.
Waxay isticmaashaa: Cilmi-baadhista bayoolajiga, dawada, waxa loo isticmaalaa xaakada kala dirida daawada iyo ka hortagga sumowga acetaminophen.
Isticmaala: Reagents biochemical, dawo, alaabtan waxa loo isticmaalaa sidii rasiiye, kaas oo la sheegay in ay fududahay in la nadiifiyo xaakada oo ay fududahay in la qufaco.Waxay saameyn ku yeelataa xaakada viscous.Habka ficilku waa in kooxda sulfhydryl ee ku jirta qaabdhismeedka molecular ee alaabtan ay jebin karaan bond disulfide Kiimikada ee silsiladda polypeptide mucin ee xaakada xabka ah, gooyaan xabka, yareeyaan viscosity ee xaakada, oo ka dhigi dareere iyo fudud qufac.Waxay ku habboon tahay cudurrada neef-mareenka ee ba'an iyo kuwa daba-dheeraada ee leh xaako qaro weyn oo ay adag tahay in la filayo, iyo sidoo kale calaamadaha muhiimka ah ee dhibka nuugista sababtoo ah xannibaadda xaddi badan oo xaako dhegdheg ah.
Isticmaalka: N-acetyl-L-cysteine waxaa loo isticmaali karaa daawo xaako-kala diri karta.Waxay ku habboon tahay xannibaadda neefsashada ee ay keento xaddi badan oo xannibaad xaako ah.Intaa waxaa dheer, waxaa sidoo kale loo isticmaali karaa sun-saaridda sunta acetaminophen.Sababtoo ah alaabtani waxay leedahay ur gaar ah, qaadashada waxay si fudud u keeni kartaa lallabbo iyo matag.Waxay leedahay saameyn soo jiidasho leh oo ku saabsan habka neefsashada waxayna keeni kartaa bronchospasm.Waxaa loo isticmaalaa in lagu daro bronchodilators sida isoproterenol iyo qalabka nuugida xaakada si loo saaro xaakada.Waa in aan lala xiriirin biraha (sida Fe, Cu), caag, oksaydhiyeyaasha, iwm. Waa inaan lala isticmaalin antibiyootiga sida penicillin, cephalosporin, tetracycline, iwm.Si taxaddar leh u isticmaal bukaannada qaba neefta bronki.
