Alaabta

3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine waa iskudhis kiimiko ah oo ay leeyihiin qoyska xanthine.Soosaarayaasha Xanthine ayaa si aad ah loo darsay waxaana lagu yaqaanaa codsiyadooda kala duwan, gaar ahaan dhanka farmashiyaha. Hal codsi oo muhiim ah 3-Methyl-7-(2-butyn-1-yl) -8-bromoxanthine waa isticmaalkeeda suurtagalka ah. daawo ahaan loogu talagalay daaweynta xaaladaha neef-mareenka sida neefta iyo cudurrada sambabada ee joogtada ah (COPD).Soosaarayaasha Xanthine, oo ay ku jiraan theophylline, ayaa muddo dheer loo isticmaali jiray daawaynta neefsashada sababtoo ah astaamaha bronchodilatory iyo anti-bararka.Iskudhisyadani waxay ku shaqeeyaan nasinta murqaha siman ee marinnada hawada waxayna yareeyaan bararka, sidaas awgeed waxay hagaajinayaan shaqada neefsashada.Ku darida atom bromine ee booska 8th ee giraanta xanthine ee 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine waxay kor u qaadi kartaa saameynteeda bronchodilatory marka la barbar dhigo kuwa kale ee xanthine.Beddelka bromine ee xeryahooda la midka ah ayaa la muujiyay inay kordhiyaan awooddooda iyo muddada ficilkooda.Sidaa darteed, xaruntan ayaa laga yaabaa inay leedahay karti waxtar leh oo dheer oo bronchodilator ah oo loogu talagalay xaaladaha neefsashada. Intaa waxaa dheer, xanthine ayaa sidoo kale la baaray sifooyinkooda neuroprotective ee suurtagalka ah.Waxay muujiyeen saamaynta antioxidant iyo anti-bararka, iyo sidoo kale awoodda kor loogu qaado socodka dhiigga maskaxda iyo hagaajinta shaqada garashada.Guryahaani waxay ka dhigaan musharaxiin xiiso leh xanuunada neurodegenerative sida Alzheimers iyo Parkinson's cudurada. Marka lagu daro codsiyada dawooyinka, 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine ayaa sidoo kale laga yaabaa in loo isticmaalo cilmi-baarista sayniska.Kala soocida Xanthine waxaa inta badan loo shaqeeyaa sidii qalab kiimiko ah si loo barto adenosine reseptors iyo phosphodiesterase enzymes.Iskudhisyadani waxay u dhaqmi karaan sida ligands ama xannibaadayaasha, iyagoo caawinaya baaritaanka hababka molecular ee gaarka ah iyo waddooyinka. U wanaaji hantideeda codsiyada gaarka ah.Fal-celin kiimiko oo kala duwan, sida beddelka, isku-darka, iyo falcelinta isku-xidhka, ayaa la adeegsan karaa si loo soo bandhigo kooxaha shaqeeya ama wax ka beddelka qaab-dhismeedka asaasiga ah.Wax-ka-beddeladani waxay awood u yeelan karaan inay kor u qaadaan hawlahooda farmasiga ama waxay awood u siin karaan horumarinta noocyada kala duwan ee xulashada xulashada iyo bioavailability. Gabagabadii, 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine waxay haysaa awood weyn oo loogu talagalay isticmaalka daawada neefsashada. , ilaalinta neerfaha, iyo cilmi-baarista biochemical.Saameynteeda bronchodilatory waxay ka dhigtaa musharax rajo leh oo loogu talagalay daaweynta xaaladaha neefsiga, iyo sifooyinka neuroprotective ee suurtogalka ah waxay soo jeedinayaan codsiyada cudurrada neurodegenerative.Cilmi-baaris dheeraad ah iyo horumarin ayaa lagama maarmaan noqon doonta in si buuxda loo sahamiyo loogana faa'iidaysto faa'iidooyinka xaruntan ee dhinacyada caafimaadka iyo sayniska ee kala duwan.