Alaabta

Xarunta 2-({(5S)-2-oxo-3-[4- (3-oxomorpholin-4-yl) phenyl] -1,3-oxazolidin-5-yl}methyl) -1H-isoindole-1, 3 (2H) -dione waa molecule organic adag oo leh codsiyada suurtagalka ah ee goobaha daawada iyo daawooyinka. Joogitaanka xudunta isoindole waxay muujinaysaa in xaruntani ay leedahay sifooyin qaabaysan oo ku habboon bayooloji oo laga helay molecules bioactive.Isoindole derivatives ayaa lagu soo warramey in ay leeyihiin sifooyin kala duwan oo farmaajo ah, oo ay ku jiraan antitumor, anti-bararka, iyo hawlaha antimicrobial.Oxazolidinones ayaa loo adeegsaday sidii qaybo muhiim ah oo ka mid ah antibiyootiga, gaar ahaan bakteeriyada u adkaysata daawada.Tani waxay soo jeedinaysaa in xaruntu ay yeelan karto awood ahaan sida bakteeriyada bakteeriyada. Joogitaanka unugyada morpholinone, oo ay matalaan 4- (3-oxomorpholin-4-yl) kooxda phenyl, waxay ku daraysaa kakanaanta isticmaalka xarunta.Morpholines ayaa si weyn loogu daray xeryahooda daawaynta sababtoo ah awoodda ay u leeyihiin inay la falgalaan bartilmaameedyada noole ee kala duwan.Kooxda oxo ee morpholinone waxay awood u yeelan kartaa inay kor u qaaddo isdhexgalka xarunta ee bartilmaameedyada gaarka ah, taasoo ka dhigaysa dhisme qiimo leh oo lagu ogaanayo daroogada iyo horumarinta. Kooxda 1,3-oxazolidin-5-yl, oo ku xiran xudunta isoindole, waxay sameysaa goobta ugu muhiimsan ee firfircoon ee xarunta.Qaab dhismeedka kiimikada gaarka ah ee kooxdani waxay soo jeedinaysaa in laga yaabo in ay la falgalaan bartilmaameedyada noolaha sida enzymes ama reseptors.Guud ahaan, oo ku salaysan qaababka qaabdhismeedka dhismaha, waxay awood u leedahay inay soo bandhigto waxqabadyada farmaajo ee bakteeriyada, anti-bararka, iyo meelaha kale ee daaweynta.Si kastaba ha ahaatee, adeegsigeeda gaarka ah iyo hababka ficilku waxay u baahan doontaa in lagu go'aamiyo daraasado dheeraad ah, oo ay ku jiraan tijaabooyinka vitro iyo in vivo, si loo qiimeeyo waxtarkeeda iyo muuqaalada badbaadada. Gebogebadii, xarunta 2-({(5S) -2-oxo -3-[4- (3-oxomorpholin-4-yl) phenyl] -1,3-oxazolidin-5-yl}methyl) -1H-isoindole-1,3 (2H) -dione waxay muujinaysaa ballanqaad dhinaca daawada iyo dawooyinka sababtoo ah qaab-dhismeedkeeda adag iyo sifooyinka dawooyinka ee suurtogalka ah.Cilmi-baarista mustaqbalka waa lagama maarmaan si loo sahamiyo isticmaalkeeda gaarka ah, codsiyada daweynta ee suurtagalka ah, iyo waxtarka guud.