Alaabta

(1S) -4,5-Dimethoxy-1-[(methylamino) methyl] benzocyclobutane hydrochloride waa xarun kiimiko ah oo soo bandhigta siyaalo xiiso leh waxayna bixisaa codsiyada suurtagalka ah ee kimistariga daawada iyo horumarinta daroogada. Xaruntani waxay ka tirsan tahay fasalka phenethylamines ee la beddelay waxayna leedahay qaabdhismeedka asaasiga ah ee benzocyclobutane.Tilmaamahan qaab-dhismeedku waxay ka dhigayaan musharax xiiso leh oo loogu talagalay horumarinta dawooyinka cusub ee lagu beegsanayo hababka noolaha ee kala duwan. Mid ka mid ah isticmaalka suurtagalka ah ee (1S) -4,5-Dimethoxy-1-[(methylamino) methyl] benzocyclobutane hydrochloride waxay ku jirtaa xiriirkeeda soo-dhoweeyayaasha qaarkood habdhiska dhexe ee neerfayaasha.Iyada oo wax laga beddelayo qaab-dhismeedkeeda, cilmi-baarayaashu waxay abuuri karaan derivatives kuwaas oo muujinaya ku-xidhka xulashada ee noocyada hoosaadyada soo-dhoweeyaha gaarka ah.Tani waxay furaysaa fursadaha helitaanka daawaynta cusub ee xaaladaha sida niyad-jabka, walaaca, iyo qabatinka.Awoodda xarunta sida serotonin agonist agonist ama antagonist ayaa la sahamiyay, taasoo soo jeedinaysa isticmaalka suurtogalka ah ee daaweynta xanuunka niyadda iyo xaaladaha kale ee dhimirka ee la xidhiidha. Intaa waxaa dheer, (1S) -4,5-Dimethoxy-1-[(methylamino) methyl] benzocyclobutane hydrochloride iyo ka-soo-saarkeedu waxay muujiyeen ballanqaad xagga cilmi-baarista maandooriyaha.Iyadoo la falgaleysa nidaamyada neurotransmitter ee maskaxda ee gaarka ah, xaruntan ayaa suurtagal ah in loo isticmaalo in lagu beddelo dariiqyada abaal-marineed ee la xidhiidha qabatinka iyo gargaarka horumarinta daawaynta cusub ee cilladaha xadgudubka mukhaadaraadka. Codsiga kale ee suurtogalka ah ee xaruntan ayaa ah waxtarkeeda qalab cilmi baaris ah cilmiga neerfaha.Qaabdhismeedkeeda gaarka ah ayaa u oggolaanaya inay la falgasho soo-dhoweyaasha neerfayaasha oo ay beddelaan sii-deynta iyo qaadashada neurotransmitter.Cilmi-baadhayaashu waxay isticmaali karaan (1S) -4,5-Dimethoxy-1-[(methylamino) methyl] benzocyclobutane hydrochloride si ay u baaraan dariiqyada calaamadaha neerfaha oo ay helaan fikrado ku saabsan hababka asaasiga ah ee cudurrada neerfaha sida Alzheimers iyo Parkinson's disease. Intaa waxaa dheer, (1S) -4,5-Dimethoxy-1-[(methylamino) methyl] benzocyclobutane hydrochloride waxay qiimo u leedahay helitaanka iyo horumarinta daroogada.Kakanaanta qaabdhismeedkeeda ayaa ka dhigaysa meel xiiso leh oo laga bilaabo isku dhafka qaybaha kiimikada cusub ee leh codsiyada daweynta ee suurtagalka ah.Iyadoo wax laga beddelayo qaab-dhismeedkeeda iyo sahaminta kala duwanaansho kala duwan, saynisyahannadu waxay sahamin karaan isdhexgalka xarunta ee bartilmaameedyada noolaha ee kala duwan waxayna suurtogal u tahay inay ogaadaan dawooyin cusub oo muujinaya waxtarka la wanaajiyey iyo waxyeellooyinka hoos u dhaca. Gabagabadii, (1S) -4,5-Dimethoxy-1-[( methylamino) methyl] benzocyclobutane hydrochloride waxay bixisaa codsiyo kala duwan oo suurtagal ah oo ku saabsan kimisteriga daawada iyo cilmiga neerfaha.Qaab dhismeedkeeda kiimikaad ee gaarka ah iyo isku xirnaanta soo-dhoweeyayaasha qaarkood ayaa ka dhigaya musharaxa rajo-gelinta ah ee horumarinta daweynta cusub ee aagagga xanuunka dhimirka ee maskaxda, qabatinka daroogada, iyo cudurrada neerfaha.Cilmi-baaris dheeraad ah iyo sahaminta xaruntan iyo ka-soo-saarkeeda ayaa awood weyn u leh horumarinta fahamka xaaladahan iyo helitaanka daawaynta cusub si loo hagaajiyo caafimaadka aadanaha.