Tetracycline hydrochloride CAS: 64-75-5 99% budada crystalline jaalaha ah
| Lambarka buugaagta | XD90366 |
| Magaca Alaabta | Tetracycline hydrochloride |
| CAS | 64-75-5 |
| Qaanuunka molecular | C22H24N2O8 · HCl |
| Miisaanka Molecular | 480.90 |
| Faahfaahinta Kaydinta | -15 ilaa -20 °C |
| Xeerka Tarifka La Iswaafajiyay | 29413000 |
Tilmaamaha Alaabta
| Gabagabo | U hoggaansan BP2013, EP7, USP38 |
| Biraha culus | <0.005% |
| Xumaanta Keliya | <0.1% |
| Aqoonsiga | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 |
| Khasaare xagga qallajinta | <2.0% |
| Walxaha haraaga ah | n-Butanol <3000ppm |
| Qiimayn | BP2013/EP7 99% |
| Sulfated Ash | <0.5% |
| Wareegga indhaha ee gaarka ah | -240 ilaa -255° |
| Awoodda | USP 38:>900ug/mg |
| Wadarta wasakhda | <5% |
| Muuqashada | Budada crystalline jaalaha ah |
| 4-epianhydrotetracycline | <2% |
| Xadka Microbial | U hogaansama |
| 4-Epiteracycline | <3% |
| Anhydrotetracyline | <0.5% |
| Chlortetracycline Hydrochloride | <0.5% |
| Haraaga Solvent | <100pm |
Horumarinta iska caabbinta antimicrobial ayaa loo qoondeeyay xad-dhaaf iyo si xun u isticmaalka wakiilada antimicrobial.Staphylococci waa qayb ka mid ah flora caadiga ah laakiin sidoo kale waa cudur-sidaha suurtagalka ah ee u adkaysta antibiyootiko badan oo la yaqaan.Iska caabbinta xinjirowga lidka ku ah staphylococci (ConS) ayaa la soo jeediyay inay horumarto sababtoo ah cadaadiska xulashada wanaagsan ka dib daaweynta antibiyootiga.Daraasadani waxay baadhis ku samaysay joogitaanka sagaalka jeermis ee inta badan loo isticmaalo kaadida bini'aadamka ee bukaan-socod ee laba cosbitaal oo ku yaal Ghana ee la xidhiidha iska caabbinta CoNS.Kaadida iyo CoNS ayaa laga qaaday muunado (n = 246 iyo n = 96 siday u kala horreeyaan) bukaannada ku jira laba cosbitaal oo ku yaal Ghana.CoNS waxaa lagu aqoonsaday iyadoo la isticmaalayo midabaynta Gram, baaritaanka xinjirowga dhiigga, iyo MALDI-TOF/MS, iyo u nuglaanta ka hortagga jeermiska 12 ee ka-hortagayaasha caadiga ah waxaa lagu go'aamiyay faafinta diskka.Waxaa intaa dheer qaab lafo-gur ah ayaa loo sameeyay si loo go'aamiyo sagaalka jeermis-dilaha ugu badan ee Ghana laga isticmaalo iyadoo la isticmaalayo soo saarista adag-ph ase oo ay weheliso HPLC-MS/MS iyadoo la isticmaalayo ionization buufin elektaroonig ah.Inta jeer ee ugu badan ee iska caabinta CoNS waxaa lagu arkay penicillin V (98%), trimethoprim (67%), iyo tetracycline (63%).S. hemolyticis ayaa ah go'doominta ugu badan (75%), waxaa ku xiga S. epidermidis (13%) iyo S. hominis (6%).S. hemolyticus ayaa sidoo kale ahaa noocyada muujinaya iska caabbinta ugu sareysa (82%).69% CoNS-ta go'doonsan waxay ahaayeen kuwo u adkaysta daawada badan (≧ 4 antibiyootik) iyo 45% ee CoNS waxay u adkaysteen methicillin.Daawooyinka lidka ku ah bakteeriyada ayaa laga helay 64% ee muunadaha kaadida ee la lafa-guray (n = 121) halkaasoo inta badan la ogaado antimicrobials ciprofloxacin (30%), trimethoprim (27%), iyo metronidazole (17%).Natiijooyinka ugu waaweyn ee daraasaddan ayaa ahaa in faafitaanka bakteeriyada la ogaaday ee kaadida ay aad uga badan tahay isticmaalka ay soo tebiyeen bukaannada iyo faafitaanka S. hemolyticus ee adkaysiga u ah ayaa aad uga badan marka loo eego noocyada kale ee CoNS ee adkaysiga u leh marka wakiilada antimicrobial laga helay kaadida.
