Alaabta

Cytometry socodka qulqulka waa hab ujeedo ah oo lagu sameeyo baaritaannada xasaasiga ah ee ka hortagga duumada ee vitro iyadoo kordhinaysa suurtagalnimada codsiga goobaha goobta.Waxaan baarnay u nuglaanta vitro ee todoba dawooyinka ka hortagga duumada 40 cusub oo P. falciparum field go'doomin iyada oo loo marayo habka cytometry socodka (FCM), midabka LDH ku salaysan ELISA: DELI), iyo falanqaynta muraayadda microscopic caadiga ah ee koritaanka.Wixii FCM ah, 184/280 (66%) imtixaannada ayaa la kulmay shuruudaha aqbalaadda falanqaynta, marka la barbar dhigo 166/280 (59%) ee DELI.Waxaa jiray heshiis wanaagsan oo u dhexeeya FCM iyo microscopy, halka DELI ay u janjeertay inay soo saarto joogtooyin xannibaadyo kala badh ka sarreeya (IC50s) marka loo eego FCM, iyada oo guud ahaan eexdu tahay 2.2-laab (isbarbardhigga Bland-Altman).Qiimaha artesunate iyo dihydroartemisinin ayaa aad u saameeyay.Kor u kaca is-daba-marineed ee calaamadda ee xajmiyada aadka u sarreeya ee mefloquine iyo xeryahooda la xidhiidha ayaa si aad ah loogu calaamadeeyay DELI assay, oo soo jeedinaysa in saamaynta bartilmaameedka ah ee wax soo saarka LDH ay masuul ka tahay.Luminta calaamada FCM sababtoo ah soo noqoshada ama korriinka gaabiska ah ayaa lagu arkay tiro yar oo muunado ah.Natiijooyinkani waxay kordhiyeen shaqadii hore ee isticmaalka cytometry socodka si loo go'aamiyo u nuglaanta ka hortagga duumada marka loo eego tirada shaybaarada, noocyada daawooyinka, iyo marka la barbardhigo hababka kale.