Streptomycin sulfate CAS: 3810-74-0 budada cad
| Lambarka buugaagta | XD90361 |
| Magaca Alaabta | Streptomycin sulfate |
| CAS | 3810-74-0 |
| Qaanuunka molecular | (C21H39N7O12)2·3H2SO4 |
| Miisaanka Molecular | 1457.39 |
| Faahfaahinta Kaydinta | 2 ilaa 8 °C |
| Xeerka Tarifka La Iswaafajiyay | 29412080 |
Tilmaamaha Alaabta
| Darajo | USP36/EP8.0 |
| pH | 4.5-7.0 |
| Khasaare xagga qallajinta | ≤7.0% |
| Qiimayn | ≥720IU/MG |
| Sulfate | 18.0 ~ 21.5% |
| Muuqashada | Caddaan ama ku dhawaad cad cad, oo aad ugu milmay biyaha, ku dhawaad aan lagu milmi karin ethanol. |
| Methanol | ≥0.3% |
| Streptomycin B | ≤3.0% |
| Tijaabada Midabka | ≥90.0% |
| Sulfuric acid | ≤1.0% |
| Maaddooyinka sodium sulfite ee xoogga leh | ≤0.4% |
Inkasta oo aetiology ee xumaanshaha disc intervertebral si liidata loo fahmo, hal hab oo looga hortago habkan ayaa laga yaabaa in la joojiyo apoptosis.Daraasadda hadda jirta, saamaynta anti-apoptotic ee karboxymethylated chitosan (CMCS) ee unugyada nucleus pulposus (NP) ayaa la baadhay iyada oo ujeedadu tahay in kor loo qaado badbaadada unugyada disc.Unugyada jiirka ee NP waa la go'doomiyay oo lagu dhaqay vitro, iyo hydrogen peroxide (H2O2) ayaa loo isticmaalay in lagu dhiso qaabka apoptosis cell NP.Jiritaanka unugyada waxaa lagu qiimeeyay xirmo-tirinta unug-8.Saamiga unugyada apoptotic-ka waxaa sahamiyay annexin V-fluorescein isothiocyanate (FITC) iyo propidium iodide (PI) falanqaynta midabaynta labajibbaaran, iyo qaab-dhismeedka waxaa lagu arkay Hoechst 33342 midabaynta.Awoodda xuubka mitochondrial ee unugyada NP waxaa lagu qiimeeyay rhodamine 123 fluorescence midabaynta.Reverse transcription (RT) - falcelinta silsiladda polymerase tirada (qPCR) ayaa la sameeyay si loo cabbiro heerarka mRNA ee nitric oxide synthase inducible (iNOS), caspase-3, B-cell lymphoma (Bcl) -2, nooca II kolajka iyo aggrecan.Falanqaynta xuubka galbeedka ayaa la sameeyay si loo ogaado heerarka borotiinka ee iNOS iyo Bcl-2.Natiijooyinka midabaynta ee V-FITC/PI iyo Hoechst 33342 waxay muujiyeen in CMCS ay awood u yeelatay inay ka hortagto unugyada NP apoptosis qaab ku tiirsan qiyaasta.Rhodamine 123 midabaynta ayaa cadaysay in CMCS ay hoos u dhigtay daciifnimada xuubka mitochondrial ee unugyada NP ee H2O2-la daweeyay.La dhimay kasbase-3 iyo dhaqdhaqaaqa Bcl-2 oo kordhay ayaa lagu ogaaday unugyada NP-da ee CMCS-ku daaweeyay RT-qPCR iyo falanqaynta western blot.CMCS waxa kale oo ay kor u qaaday fidinta iyo dheecaanka nooca II kolajka iyo aggrecan ee unugyada NP-da ee H2O2.CMCS ayaa la tilmaamay inay waxtar u leedahay ka hortagga dhimashada unugyada apoptotic ee vitro, taasoo muujinaysa faa'iidooyinka suurtagalka ah ee habkan daweynta ee lagu xakameynayo xumaanshaha saxanka.
