Alaabta

Galactosidase waxa loola jeedaa qayb ka mid ah ensaymes kuwaas oo hydrolyzed walxaha ka kooban galactosidic bonds, sida lactose (lactose waa disaccharide ah oo ay samaysay uumi fuuqbax ee hal molecule of glucose iyo hal molecule of galactose).Inta badan waxaa loo qaybiyaa α-galactosidase iyo β-galactosidase.α-Galactosidase waxay kicisaa hydrolysis of α-galactosidase bonds, kaas oo bedeli kara oo dumin kara arrimaha ka-hortagga nafaqeynta α-galactosides ee quudinta iyo cuntada soyka, oo wanaajisa nuxurka nafaqada.Intaa waxaa dheer, insaymku wuxuu kaloo leeyahay codsiyo gaar ah oo ku saabsan daawooyinka, farsamaynta dhumucda iyo warshadaha waraaqaha.β-Galactosidase ma aha oo kaliya in aad iyo aad loogu isticmaalo warshadaha cuntada, laakiin sidoo kale waxay door muhiim ah ka ciyaaraa dhinacyada biotechnology sida injineernimada hidde, injineernimada enzyme, injineernimada borotiin, iwm, oo bilaabay in si weyn loogu isticmaalo daawada. iyo goobo kale.

α-galactosidase (α-galactosidase, α-gal, EC 3.2.1.22) waa exoglycosidase ah kaas oo kicinaya hydrolysis of α-galactosidic bonds, waxaana sidoo kale loo yaqaan melibiase sababtoo ah waxay dumin kartaa melibiose, taas oo kicinaysa hydrolysis ee α-galac curaartaHabkani wuxuu faa'iido u leeyahay hagaajinta iyo baabi'inta nafaqooyinka ka-hortagga ah ee ku jira quudinta iyo cuntooyinka soyka.Intaa waxaa dheer, waxay xaqiijin kartaa B → O beddelka kooxda dhiigga ee goobta caafimaadka, diyaariso nooca dhiigga ee caalamiga ah, iyo sidoo kale door muhiim ah ka ciyaara daaweynta beddelka enzyme ee cudurka Fabry.Alpha-galactosidase sidoo kale waxay ku dhaqmi kartaa polysaccharides adag, glycoproteins iyo sphingolipids oo ay ku jiraan curaarta alfa-galactosidic.Qaar ka mid ah enzymes α-galactosidase waxay sidoo kale leeyihiin saameynta transgalactosylation marka xoojinta substrate aad loo kobciyo, taas oo loo isticmaali karo isku-darka oligosaccharides iyo diyaarinta derivatives cyclodextrin.Horumarinta neutrophilic ama pH-stable α-galactosidase iyo raadinta microorganisms ama dhirta leh wax soo saarka enzyme sare waxay noqdeen goob cilmi baaris ah sanadihii ugu dambeeyay.Qaar badan oo ka mid ah α-galactosidases thermostable ayaa sidoo kale si tartiib tartiib ah u soo jiitay xiisaha ballaaran ee saynisyahano sababo la xiriira sifooyinkooda gaarka ah, iyagoo rajeynaya inay isticmaalaan heerkulbeeggooda si ay door weyn uga ciyaaraan codsiyada warshadaha, iyo sidoo kale inay muujiyaan codsi ballaadhan oo ku saabsan dhinacyada sayniska iyo tignoolajiyada iyo daawada.rajada codsiga.