Jiirka ayaa la maamulay hal dose oo ah asal ahaan dhirta phenolic antioxidant Quercetin (QC) oo bilaash ah, liposome ku daboolan iyo foomamka liposome galactosylated 2 h kahor qiyaasta hepatotoxic ee carbontetrachloride (CCl4, 40% v / v ee saliid saytuun ah, 1 ml / kg b) .wt).Ka mid ah saddexda nooc ee kala duwan ee QC la tijaabiyay, kaliya galactosylated liposomal QC ayaa siisay difaac weyn oo ka dhan ah CCl4 oo ay sababtay dhaawaca beerkaKadib 24 h ee duritaanka (SC) unugyada hepatic ee jiirka ayaa la helay inay u nugul yihiin CCl4 waxyeelada oksaydhiyaha waxaana lagu kormeeray tirada korodhka ah ee diene isku dhafan ee xuubka beerka.Kordhinta laba-laaban ee diene isku-dhafan ee kicinta CCl4 ayaa hoos loo dhigay ilaa heer caadi ah daawaynta hore ee lipsomal-ka ee galactosylated.Carbontetrachloride waxay sababtay dhaawaca xuubabka ee unugyada hepatic waxaana lagu qiimeeyay serum dhiiga iyo unugyada beerka baaritaanka histopathological.Dhaawaca xuubabka ee soo saarista CCl4 ayaa lagu sii qiimeeyay heerka hoos u dhaca ee xuubka balasaha (PM) ee ku xiran enzyme Na +/K+ ATPase waxqabadka waxaana lagu kordhiyay kaliya daaweynta hore ee lipsomal galactosylated lipsomal QC.Carbontetrachloride waxay keentay hoos u dhac la taaban karo labadaba heerarka enzymatic iyo molecular endogenous antioxidant ee unugyada hepatic.Niyad jabka nidaamka antioxidant ee unugyada hepatic waxaa si buuxda uga hortagay hal dose oo ah lipsosomal galactosylated QC kahor daawaynta CCl4.Qaadashada beerka ee QC ayaa la qiyaasay ka dib 2 h ee duritaanka flavonoid (8.9 micromol/kg miisaanka jidhka) (bilaash ama foomamka liposomal) iyo 85% ee QC la duray ayaa laga helay beerka kiiska galactosylated liposomal QC.Halka 25% kaliya ee qiyaasta la isku duro laga helay beerka markii qadar isku mid ah oo QC ah oo bilaash ah lagu muday.Carbontetrachloride waxay sidoo kale keentay isbeddel ku yimaada dareeraha xuubka waxaana lagu qiimeeyay hoos u dhaca xuubka micro-viscosity.Daawaynta hore ee QC ee bilaashka ah waxay keentay in aan laga ilaalin CCl4 ay keentay kororka dheecaanka xuubka beerka, halka galactosylated liposomal QC uu sameeyay difaac weyn oo ka dhan ah kororka.Natiijooyinka daraasaddan ayaa shaaca ka qaaday in QC ee liposome galactosylated ay sameyn karto difaac weyn oo ka dhan ah dhaawaca hepatocellular ee CCl4.
