Alaabta

N (ε) -trifluoroacetyl-L-lysine waa soosaar gaar ah oo ka mid ah amino acid lysine, halkaasoo epsilon (ε) kooxda amino ay ilaaliso koox trifluoroacetyl (TFA).Xaruntani waxay ka heleysaa codsi meelo kala duwan, gaar ahaan isku-dhafka peptide iyo cilmi-baarista biochemical. Mid ka mid ah isticmaalka weyn ee N (ε) -trifluoroacetyl-L-lysine ayaa ku jira isku-dhafka peptide-wajiga adag (SPPS).Peptides-ku waxay door muhiim ah ka ciyaaraan habab badan oo bayooloji ah, isku-dubbaridooduna waxay u baahan tahay isu-ururinta isku-xiga ee amino acids.Kooxda ilaalinta TFA ee kooxda epsilon amino ee lysine waxay ka hortagtaa falcelinta aan loo baahnayn inta lagu jiro samaynta dammaanadda peptide-ka iyadoo u oggolaanaysa asiidhyada amino-yada kale inay ku lammaanaadaan boosaska la rabo.Marka shirka peptide la dhammeeyo, kooxda ilaalinta TFA si xushmad leh ayaa laga saari karaa, iyo N (ε) -trifluoroacetyl-L-lysine hadhaaga ayaa la sii dheereyn karaa si loo soo saaro taxane peptide gaar ah.N (ε) -trifluoroacetyl-L-lysine sidoo kale waa loo adeegsaday cilmi-baadhista biochemical si loo barto qaab-dhismeedka borotiinka, shaqada, iyo isdhexgalka.Waxay u adeegi kartaa sidii qalab lagu baaro doorka hadhaaga lysine ee isdhexgalka borotiinka-protein, isdhexgalka borotiinka-DNA, iyo wax ka beddelka ka dib tarjumaada.Marka la soo bandhigo kooxda TFA, sifooyinka kiimikada ee lysine waa la bedeli karaa, taas oo u oggolaanaysa baaritaanka hababka lysine-dhexdhexaadinta gaarka ah ee hababka bayoolojiga. Intaa waxaa dheer, N (ε) -trifluoroacetyl-L-lysine waxay sidoo kale ka heli kartaa codsiga horumarinta bartilmaameedka. hababka gaarsiinta daroogada.Marka la isku daro wakiilada daweynta gaarka ah ee haraaga lysine iyada oo loo marayo kooxda TFA, waxaa suurtogal ah in la kordhiyo xasilloonida iyo xulashada daroogada, taasoo horseedaysa waxtarka la xoojiyay iyo hoos u dhaca waxyeellooyinka.Istaraatiijiyadan ayaa lagu sahamiyay bixinta daawooyinka ka hortagga kansarka, antibiyootiga, iyo daaweynta kale. Marka lagu daro codsiyadeeda tooska ah, N (ε) -trifluoroacetyl-L-lysine sidoo kale waxaa loo isticmaali karaa dhismo dhisme ah oo loogu talagalay isku-dhafka xeryahooda kale ee shaqeynaya. .Qaab dhismeedka kiimikada ee gaarka ah iyo falcelinta waxay ka dhigtaa wax soo jiidasho leh oo bilaw ah ama dhexdhexaad ah isku-dhafka molecules organic adag, oo ay ku jiraan daawooyinka, agrochemicals, iyo alaabta. Si kastaba ha ahaatee, waa muhiim in la xakameeyo N (ε) -trifluoroacetyl-L-lysine si taxadar leh, iyadoo la raacayo taxaddarrada habboon ee badbaadada.Waxaa lagu talinayaa in lagu shaqeeyo shaybaar hawo wanaagsan leh oo aad isticmaasho qalabka ilaalinta shakhsi ahaaneed ee habboon, sida galoofyada iyo muraayadaha badbaadada. Marka la soo koobo, N (ε) -trifluoroacetyl-L-lysine waa soosaar qiimo leh oo lysine ah oo ka hela codsiyada kala duwan ee peptide. synthesis, cilmi-baarista biochemical, gaarsiinta daroogada la beegsaday, iyo isku-dhafka organic.Awooddeeda lagu ilaaliyo kooxda amino epsilon ee lysine waxay u oggolaaneysaa isku-dhafka saxda ah ee peptide, halka alaabteeda kiimikaad ee la beddelay ay awood u siiso daraasadda hababka dhexdhexaadinta lysine.Marka si habboon loo maareeyo, N (ε) -trifluoroacetyl-L-lysine waxay caddaynaysaa inay tahay qalab waxtar u leh codsiyada sayniska iyo warshadaha kala duwan.