Alaabta

Methyl 1,2,3,4-tetra-O-acetyl-β-D-glucuronate ayaa loo isticmaalay daraasad lagu qiimeynayo naqshadeynta iyo isku dhafka glucuronide-ka-soo-baxa biyaha ee kaamtoothecin ee prodrμg monotherapy iyo prodrμg enzyme-ka-hortagga jidhka daawaynta.Waxa kale oo loo isticmaalay daraasad si loo baadho isku-dhafka iyo doorka heterocycles glycosylthio ee kiimikada karbohaydraytyada.

Isku-dubarid walxaha ka soo jeeda pentopyranic acid

N4-Benzoylcytosine 1- (methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate) ayaa lagu helay wax-soo-saarka 70% by glycosylation of trimethylsilyl derivative ee N4-benzoylcytosine leh methyl 1,2 ,3,4-tetra-O-acetyl-β-D-glucopyranuronate iyadoo ay joogaan saddex qaybood oo u dhiganta SnCl4 oo ah wakiilka isku-xidhka ah.Cytosine 1- (β-D-glucopyranosiduronamide) (IV) - amide ee pentopyranic acid - ayaa lagu soo koobay wax-soo-saarka ficil ahaan qiyaas ahaan ammonolysis ee nucleoside (I).