L-Histidine Cas: 71-00-1 98.5% crystals cad ama budada crystalline
Lambarka buugaagta | XD90301 |
Magaca Alaabta | L-Histidine |
CAS | 71-00-1 |
Qaanuunka molecular | C6H9N3O2 |
Miisaanka Molecular | 155.15 |
Faahfaahinta Kaydinta | Ambient |
Xeerka Tarifka La Iswaafajiyay | 29332990 |
Tilmaamaha Alaabta
Qiimayn | 98.5% min |
Muuqashada | Kiristaalo cad ama budada crystalline |
Darajo | USP39 |
Wareegid gaar ah | +12.6 ° ilaa +14.0 ° |
Aqoonsiga | nuugista infrared |
pH | 7.0 - 8.5 |
SO4 | <=0.03% |
Fe | <= 30ppm |
Khasaare xagga qallajinta | <=0.2% |
Hadhaaga dabka | <=0.1% |
Cl | <=0.05% |
Biraha culus (PB) | <=15pm |
Isku-dhafka la xiriira | In aan ka badnayn 0.5% wasakh kasta oo shakhsi ah ayaa la helaa;In aan ka badnayn 2.0% wadarta wasakhda ayaa la helaa |
isaga oo afar-ruplex ah oo samaysa taxanaha G-hodanka ah ayaa si aan sinnayn ugu qaybsan guud ahaan genome-ka aadanaha.Kobcinta ay ku leeyihiin dhiirrigeliyeyaasha oncogenic iyo telomeres waxay keentay xiisaha lagu beegsanayo G-quadruplex (GQ) ee daaweynta kansarka ka hortagga.Halkan, waxaan ku soo bandhigaynaa falanqaynta tirada ee jaangooyooyinka iyo dhaqdhaqaaqa GQ samaynta isku xigxiga oo lagu cabbiray fluorescence hal unugyo ah.Intaa waxaa dheer, waxaan la xiriirnay guryahan GQ bartilmaameedka ligands iyo G4 xallinta 1 (G4R1) xiritaanka borotiinka.Natiijadeenu waxay muujinaysaa in labada loop (qaybaha aan G) dhererka iyo isku xigxiga ay gacan ka geystaan is-waafajinta GQ.Raad raadadka hal unug ee wakhtiga dhabta ah waxay muujinayaan in dhaq-dhaqaaqa laalaabku uu sidoo kale ku xidhan yahay halabuurka loopka.Waxaan muujineynaa in GQ-dejinta molecules yaryar, N-methyl mesoporphyrin IX (NMM), analooggeeda, NMP iyo borotiinka G4R1 ay si xushmad leh ugu xiran yihiin isbarbardhigga GQ.Natiijooyinkayagu waxay tilmaamayaan kakanaanta isku-laabashada GQ ee lagu maamulo dhererka wareegga iyo isku xigxiga iyo sida u qaabaynta GQ ay u go'aamiso molecule-ka yar iyo borotiinka xidhitaanka.