Hygromycin B CAS: 31282-04-9 buff buff
Lambarka buugaagta | XD90374 |
Magaca Alaabta | Hygromycin B |
CAS | 31282-04-9 |
Qaanuunka molecular | C20H37N3O13 |
Miisaanka Molecular | 527.52 |
Faahfaahinta Kaydinta | 2 ilaa 8 °C |
Xeerka Tarifka La Iswaafajiyay | 2941900000 |
Tilmaamaha Alaabta
Biraha culus | 20mg/kg ugu badnaan |
pH | 7-9.5 |
Qiimayn | 99% |
Khasaare xagga qallajinta | 5% ugu badnaan |
hawlqabad | 950u/mg daq |
Amooniyam | 1% ugu badnaan |
Dambaska sulfated | 5% ugu badnaan |
Muuqashada | budada buff |
Daahirnimada TLC | >90% |
Unugyada khamiirka ee gabowga ayaa caadi ahaan loo adeegsadaa tusaale ahaan gabowga unugyada bini'aadamka ka dambeeya.Khamiirka Saccharomyces cerevisiae ee ku koray gulukooska iyadoo ay jirto ammonium sulphate ayaa inta badan loo adeegsadaa cilmi-baarista gabowga khamiirka.Waxaan falanqeeyay gabowga taariikhiga ah ee khamiirka Hansenula polymorpha oo lagu koray xaaladaha u baahan dheef-shiid kiimikaad aasaasiga ah ee koritaanka.The chronological lifespan of H. polymorpha ayaa si xoog leh loo wanaajiyey marka unugyada lagu koray methanol ama ethanol, metabolized by peroxisome enzymes, marka loo eego koritaanka gulukooska taas oo aan u baahnayn peroxisomes.Cimriga gaaban ee H. polymorpha ee gulukooska waxaa ugu wacan aashitada dhexdhexaadka ah, halka ay u badan tahay in ROS aysan door muhiim ah ka ciyaarin.Kobaca unugyada methanol/methylamine halkii ay ka ahaan lahaayeen methanol/ammonium sulphate waxa ay keentay korodhka cimriga.Tani waxay ahayd mid aan xidhiidh la lahayn aysidhka dhexdhexaadka ah.Waxaan tusineynaa in oksaydheynta methylamine ee peroxisomal amine oxidase ee xaaladaha gaajada kaarboon ay mas'uul ka tahay kordhinta nolosha.Badeecada oxidation methylamine formaldehyde ayaa sii kordhaysa taasoo keentay jiilka NADH, taas oo gacan ka geysata kordhinta jiilka ATP iyo hoos u dhigista heerarka ROS ee marxaladda taagan.Waxaan ku soo gabagabeyneynaa in dheef-shiid kiimikaadka aasaasiga ah ee peroxisome uu kor u qaaday muddada nolosha ee H. polymorpha.Waxaa intaa dheer, suurtogalnimada in lagu dhaliyo NADH xaaladaha gaajada kaarboonka ee ilaha nitrogen organic waxay taageertaa kordhin dheeraad ah ee cimriga unugyada.Sidaa awgeed, tarjumaadda falanqaynta CLS ee khamiirka waa inay ku jiraan saamaynta suurtagalka ah ee heerka tamarta unugga.