Alaabta

Isdhexgalka u dhexeeya dawada antidiabetic, Metformin iyo calf thymus DNA (CT-DNA) ee (50mM Tris-HCl) kaydinta ayaa lagu daraaseeyay nuugista UV-Muuqaalka, fluorescence, CD spectroscopy iyo cabbirada viscosity.Daraasadaha fluorimetric, enthalpy iyo entropy ee falcelinta u dhaxaysa daroogada iyo CT-DNA waxay muujisay in falcelintu ay tahay mid ka baxsan (ΔH = -35.4522 kJ mol (-1); ΔS = -49.9523 J mol (-1) K (-1). )).Daraasadaha tartanka tartanka ayaa muujiyay in daawadu ay sii deyn karto Hoechst 33258 si buuxda.Qalabku wuxuu muujiyay hyperchromism nuugista spectrum UV-Vis oo leh DNA.Xisaabinta joogtada ah ee xidhitaanka, K (b), oo laga helay daraasadaha nuugista UV-Vis waxay ahayd 8.3 × 10 (4) M (-1).Waxaa intaa dheer, isbeddellada ku jira spectra CD-ga ee joogitaanka daroogada ayaa muujinaya xasilinta qaabka B ee CT-DNA ee midigta.Ugu dambayntii, cabbiraadaha viscosity waxay daaha ka qaadeen in isku xidhka dhismaha ee CT-DNA uu noqon karo xidhid dusha sare ah, badi ahaan sababtu tahay xidhidhiyaha jeexdin. Xuquuqda daabacaada