Glutathione waxaa la dhimay Kaska: 70-18-8 98-101% Cad oo aan midab lahayn
| Lambarka buugaagta | XD90284 |
| Magaca Alaabta | Glutathione waa la dhimay |
| CAS | 70-18-8 |
| Qaanuunka molecular | C10H17N3O6S |
| Miisaanka Molecular | 307.32 |
| Faahfaahinta Kaydinta | 2 ilaa 8 °C |
| Xeerka Tarifka La Iswaafajiyay | 29309098 |
Tilmaamaha Alaabta
| Qiimayn | 98% - 101% |
| Muuqashada | Budada crystalline cad |
| Darajo | EP 7.0 |
| Xumaanta A | <0.5% |
| Xumaanta B | <0.5% |
| Biraha culus | <10ppm |
| Bakteeriyada endotoxin | <0.10EU/mg |
| Xumaanta C | <1.5% |
| Xumaanta D | <1.0% |
| Khasaare xagga qallajinta | <0.5% |
| Solubility | Si xor ah ugu milmay biyaha, waxoogaa ku milmay ethanol iyo methylene chloride |
| Birta | <10ppm |
| Chlorides | <200pm |
| Muuqashada Xalka | Cad oo aan midab lahayn |
| Wareegga indhaha ee gaarka ah | -15.5 ilaa -17.5 |
| Wadarta wasakhda | <2.5% |
| Amooniyam | <200pm |
| Dambaska sulfated | <0.1% |
| Sulfates | <300pm |
| Xumaanta E | <0.5% |
Waxka bedelka borotiinka ka dib, sida fosforyaalka tyrosine, nidaamiya isdhexgalka borotiinka-protein (PPIs) ee muhiimka u ah habaynta calaamadaha iyo noocyada unugyada gacanta.Waxaanu kordhinay khamiir la aasaasay oo laba-isku-dhafan ah oo ka shaqeeya kinases borotiinka bini'aadamka si loo falanqeeyo fosfo-tyrosine (pY) -ku-tiirsanaanta PPIs ee tijaabo toos ah, hab baaxad weyn.Waxaan aqoonsannay 292 oo u badan kuwa cusub ee pY-ku-tiirsan PPIs kuwaas oo muujiyay gaar gaar ah marka loo eego kinases iyo borotiinada isdhexgalka waxayna ansixiyeen jajab weyn oo tijaaboyin is-difaacid ah oo ka yimid unugyada naasleyda.Qiyaastii lix meelood meel ka mid ah isdhexgalka ayaa lagu dhex dhexaadiyaa motifyada isku xigxiga ee toosan ee la yaqaan halka inta badan pY-PPI ay dhexdhexaadiyaan qaybo kale oo toosan ama ay maamulaan habab aqoonsi oo kale.Falanqaynta shabakadu waxay daaha ka qaaday in dhacdooyinka aqoonsiga pY-dhexdhexaadin ay ku xidhan yihiin cutubka borotiinka oo aad ugu xidhan oo u heellan calaamadaynta iyo dariiqyada koritaanka unugyada ee la xidhiidha kansarka.Isticmaalka tijaabooyinka xidhitaanka, borotiinku waxay dhamaystiraan tayeynta iyo akhrinta phenotypic si loo astaameeyo isdhexgalka pY-ku-tiirsanaanta ee TSPAN2 (tetraspanin 2) iyo GRB2 ama PIK3R3 (p55γ), waxaan si tusaale ah u bixinaa caddaynta in labada PY-ku-tiirsanaanta PPI ay tilmaamayaan noocyada kansarka unugyada.
