(2S,3R)-2-Amino-3-hydroxybutanoic acid Cas: 72-19-5 99% budada crystalline cad
| Lambarka buugaagta | XD90285 |
| Magaca Alaabta | (2S,3R)-2-Amino-3-hydroxybutanoic acid |
| CAS | 72-19-5 |
| Qaanuunka molecular | C4H9NO3 |
| Miisaanka Molecular | 119.11916 |
| Faahfaahinta Kaydinta | Ambient |
| Xeerka Tarifka La Iswaafajiyay | 29225000 |
Tilmaamaha Alaabta
| Qiimayn | 99 - 101% |
| Muuqashada | Budada crystalline cad |
| Wareegid gaar ah | -27.5 ilaa -29.0 |
| Biraha culus | 10pm ugu badnaan |
| AS | ugu badnaan 10ppm |
| pH | 5.2 - 6.5 |
| SO4 | <0.020% |
| Fe | ugu badnaan 10ppm |
| Khasaare xagga qallajinta | <0.20% |
| Hadhaaga dabka | <0.10% |
| Gudbinta | NLT 98% |
| Cl | <0.02% |
| Ammonium cusbo | <0.02% |
Fosfatases borotiinka Serine/threonine ayaa lagu sifeeyay bakteeriyo badan oo pathogenic ah inay yihiin enzymes lagama maarmaanka ah ee ku lug leh dariiqyada gudbinta calaamadaha fosforyaalka-ku-tiirsanaanta oo inta badan lala xiriiriyo fayraska noolahaan.Baadhitaanka Mycoplasma synoviae genome ayaa daaha ka qaaday joogitaanka hiddo-wadaha (prpC) ee ku dhejinaya fosfatase borotiinka abuurka ah ee fosfatase borotiinka 2C (PP2C) hoose.Halkan, waxaan ku soo wargelineynaa sifada biochemical oo dhamaystiran ee M. synoviae phosphatase (PrpC) iyo doorka gaarka ah ee ions birta ee xiriirka qaab-dhismeedka-shaqo ee ensaymkan.Falanqaynta isku xigxiga amino acid PrpC ayaa shaaca ka qaaday in dhammaan hadhaaga ku lug leh xarunta birta dinuclear-ka iyo hadhaaga isku-dubbaridka birta saddexaad, oo lagu keydiyay phosphatases PP2C, ay ku jiraan PrpC.PrpC waa borotiin monomeric ah oo awood u leh inuu defosphorylate substrates fosfooraska iyadoo ku tiirsanaanta Mn(2+) ions.Falanqaynta xasilloonida kulaylka ayaa muujisay xasilloonida ensaymka heerkulka khafiifka ah iyo soo-noqoshada Mn(2+) ee hantidan.Falanqaynta spectrometry mass waxay soo jeedisay in saddex ion bir ah ay ku xidhmaan PrpC, laba ka mid ah kuwaas oo leh xiriir sare oo joogto ah oo muuqda.Falanqaynta is-dhaafsiga ee hadhaaga isku-dubbaridka birta saddexaad, Asp122 iyo Arg164, ayaa shaaca ka qaaday in kala duwanaanshahan ay muujiyeen isku xidhka daciifka ah ee ion manganese, iyo in labadaba isbeddellada ay saameeyeen dhaqdhaqaaqa fosfatase PrpC.Marka loo eego natiijooyinkaan, PrpC waa xubin fosphatase borotiin ah oo ku tiirsan birta oo leh xasillooni soo hagaagtay qaabka holo iyo Asp122, oo ay suurtogal tahay in ay ku lug leedahay goobta saddexaad ee birta-xidhka ah, oo lagama maarmaan u ah dhaqdhaqaaqa kicinta.
