Joogitaanka 2.8 mM D-glucose, beta-D-glucose pentaacetate (1. 7 mM) insulin la kordhiyay oo laga sii daayo jasiiradaha dooliga ee go'doonsan in ka badan alfa-D-glucose pentaacetate.Sidoo kale, korodhka dheeraadka ah ee soosaarka insulinta ee ay kicisay nateglinide (0.01 mM) ayaa ka sarraysay jasiiradaha ay soo gaadhay beta-halkii alfa-D-glucose pentaacetate.Si ka duwan, joogitaanka 2.8 mM D-glucose aan la nadiifin, alfa-L-glucose pentaacetate, laakiin aan ahayn beta-L-glucose pentaacetate, waxay si weyn u kordhisay soosaarka insulinta.Awoodda sare ee insulinotropic ee beta-anomer ee D-glucose pentaacetate waxay ku soo beegantay xaqiiqda ah inay si weyn u kordhisay saamiga lammaane ee u dhexeeya D-[U-14C]glucose oxidation iyo D-[5-3H] isticmaalka gulukoos, halka alfa-D -glucose pentaacetate wuu ku guuldareystay inuu sidaas sameeyo.Natiijooyinkaan waxaa loo fasiray inay taageeraan fikradda ah in kicinta insulin-ta ay sii daayaan esters-yadan ay inta badan u sabab tahay is-dhexgalka tooska ah ee soo-dhoweeyaha stereospecific, oo doorbidaya qaabeynta C1 ee caadiga ah beta-D-glucose pentaacetate iyo alfa-L- gulukoos pentaacetate.
