Doxycycline hyclate CAS: 24390-14-5 99% budada crystalline jaalaha ah
| Lambarka buugaagta | XD90368 |
| Magaca Alaabta | Doxycycline hyclate |
| CAS | 24390-14-5 |
| Qaanuunka molecular | C22H24N2O8·HCl·0.5C2H6O·0.5H2O |
| Miisaanka Molecular | 512.94 |
| Faahfaahinta Kaydinta | 2 ilaa 8 °C |
| Xeerka Tarifka La Iswaafajiyay | 29413000 |
Tilmaamaha Alaabta
| Xumaanta A | <2% |
| wasakhnimoB | <2% |
| Wareegid gaar ah | -105 ilaa -120 |
| pH | 2-3 |
| Xumaanta C | <0.5% |
| wasakhnimoD | <0.5% |
| Khasaare xagga qallajinta | 1.4-2.8% |
| Qiimayn | 99% |
| Hadhaaga dabka | <0.4% |
| nuugista | 300-335 |
| Wax kasta oo kale oo wasakh ah | <0.5% |
| Muuqashada | Budada crystalline jaalaha ah |
| Xumaanta F | <0.5% |
| wasakhnimoE | <0.5% |
| Khamriga Ethyl | 4.5 - 6% |
| Nuugista wasakhnimada | <0.07% |
Samaynta biofilm ee ku-meel-gaadhka ilkuhu waxay u horseedi kartaa peri-implant xuubka iyo peri-implantitis-ka xiga.Kiisaskan waxa lagu daweeyaa dawooyin antibiyootik ah sida doxycycline (Doxy).Halkan waxaan ku isticmaalnay habka korantada kiimikaad ee polarization cathodic si aan ugu dahaadhino Doxy dusha sare ee alaabta ilkaha.Dusha Doxy-dahaarka leh waxay muujisay soo dayn dilaac ah oo ku jirta cusbada fosfat-buffered intii lagu jiray 24kii saac ee hore.Si kastaba ha ahaatee, qadar aad u badan oo Doxy ah ayaa ku hadhay dusha sare ugu yaraan 2 toddobaad gaar ahaan muunad 5mA-3 h oo leh qadar sare oo Doxy ah, taas oo soo jeedinaysa labadaba suurtogalnimada bacteriostatic ee bilawga iyo muddada dheer ee dusha daboolan.Kiimikada dusha sare waxaa lagu falanqeeyay raajada sawir-qaadista sawirka iyo spectrometry ion mass spectrometry.Sawir-gacmeedka dusha sare waxaa lagu qiimeeyay iskaanka qiiqa hawada ee mikroskoobyada elektarooniga ah iyo astaanta buluug-light.Wakhti dheer oo polarization min 1 h ilaa 5 h iyo cufnaanta hadda ka sareysa ee 1 ilaa 15 mA cm(-2) waxay keentay qadar sare oo Doxy ah dusha sare ee sare.Dusha sare waxaa lagu daboolay lakabka Doxy in ka yar 100 nm iyada oo aan isbeddel weyn lagu samayn dusha sare.Hantida bakteeriyada ee dusha Doxy-dahaarka leh ayaa lagu falanqeeyay biofilm iyo qiimaynta koritaanka planktoikada iyadoo la adeegsanayo Staphylococcus epidermidis.Shaybaarada dahaarka leh ee Doxy-da ah waxay hoos u dhigeen ururinta biofilm iyo koritaanka planktonic ee dhaqanka maraq, iyo sidoo kale waxay hakiyeen korriinka bakteeriyada ee taarikada agagaarka.Saamaynta bakteeriyada ayaa ka xoog badnayd muunado 5 mA-3 h oo lagu dahaadhay qadar sare oo Doxy ah marka la barbar dhigo 1 mA-1 h.Sidaa darteed, dusha sare ee ku dahaaran Doxy waxay leedahay karti ay uga hortagto gumeysiga bakteeriyada marka ay soo gaarto godka afka.Doxy-coating waxay noqon kartaa hab macquul ah oo lagu xakameeyo xuubka xuubka-implant-ka loogana hortago u gudbidda peri-implantitis.
