D-Valine Cas: 640-68-6 C5H11NO2
| Lambarka buugaagta | XD90291 |
| Magaca Alaabta | D-Valine |
| CAS | 640-68-6 |
| Qaanuunka molecular | C5H11NO2 |
| Miisaanka Molecular | 117.14634 |
| Faahfaahinta Kaydinta | Heerkulka qolka |
| Xeerka Tarifka La Iswaafajiyay | 29224995 |
Tilmaamaha Alaabta
| Qiimayn | 99% |
| Muuqashada | budo cad |
| Cufnaanta | 1.2000 (qiyaas) |
| barta dhalaalaysa | >295°C (sbl.) (iftiin) |
| Barta karkarinta | 213.6 °C at 760 mmHg |
| Barta toosan | 83℃ |
| Tusmada dib-u-celinta | -27 ° (C=8, 6mol/L HCl) |
| Solubility | 56 g/L (20°C) |
| Biyuhu milma | 56 g/L (20ºC) |
| PSA | 63.32000 |
| LogP | 0.75460 |
| Wareegid gaar ah | -27.5º (c=5, 5N HCl) |
| Dhaqdhaqaaqa indhaha | [α]23/D -32.0 ilaa -24.0°, c = 8 gudaha 6 M HCl |
Haweenka qaba xanuunka 'antiphospholipid syndrome' (APS) waxay halis dheeraad ah ugu jiraan luminta uurka soo noqnoqda (RPL) iyo preeclampsia.Unugyada Antiphospholipid (aPL) waxay si toos ah u beddelaan shaqada trophoblast.Daawaynta heparin miisaan yar (LMWH) waxay yaraynaysaa halista RPL laakiin ma aha preeclampsia.Waxaa intaa dheer, LMWH waxay kicisaa trophoblast sFlt-1, oo ah arrin ka hortagga angiogenic oo la xiriirta preeclampsia.Maadaama fitamiin D-yarida ay la xiriirto APS iyo preeclampsia, daraasaddan ayaa raadineysay in la go'aamiyo saameynta fitamiin D-ga ee shaqada trophoblast ee goobta aPL iyo LMWH.A bini'aadamka trimester trophoblast cell (HTR8) iyo dhaqamada trophoblast aasaasiga ah ayaa lagu daaweeyay ama iyada oo aan lahayn aPL joogitaanka iyo maqnaanshaha fitamiin D, LMWH ama labadaba.Dheecaannada trophoblast ee cytokines bararka iyo angiogenic arrimood ayaa lagu qiyaasay ELISA.Vitamin D oo keliya ama marka lagu daro LMWH waxay hoos u dhigtay jawaab-celinta trophoblast ee aPL ee unugyada HTR8 iyo dhaqamada asaasiga ah.Inkasta oo fitamiin D-ga uusan wax saameyn ah ku yeelan isbeddelka dhexdhexaadinta aPL-ku-dhex-dhexaadka ah ee arrimaha angiogenic ee trophoblast asaasiga ah, waxay si weyn u joojisay sii-deynta LMWH-ku-daba-galka sFlt-1. LMWH marka lagu daro fitamiin D-ga ayaa laga yaabaa inay ka faa'iido badan tahay daaweynta hal-wakiilada ah iyadoo laga hortagayo aPL -induced trophoblast caabuq iyo dib u celinta dheecaanka LMWH-ay keentay sFlt-1.
