Cytidine Cas: 65-46-3 Budada crystalline cad 99%
Lambarka buugaagta | XD90586 |
Magaca Alaabta | Cytidine |
CAS | 65-46-3 |
Qaanuunka molecular | C9H13N3O5 |
Miisaanka Molecular | 243.22 |
Faahfaahinta Kaydinta | Ambient |
Xeerka Tarifka La Iswaafajiyay | 29349990 |
Tilmaamaha Alaabta
Muuqashada | Budada crystalline cad |
Qiimayn | 99% |
Biraha culus | <20ppm |
Foomamka Kiimikada | C9H13N3O5 |
Khasaare xagga qallajinta | <0.5% |
Hadhaaga dabka | <0.10% |
Sahayda gacanta ee triphosphates deoxynucleoside (dNTPs) ayaa muhiim u ah taranka iyo hagaajinta DNA-da.Daraasaddan, waxaan ku baarnay doorka CMP/UMP kinase (CMPK), enzym kataliya sameynta CDP, hagaajinta DNA-da.Garaacista CMPK waxay dib u dhigtaa hagaajinta DNA-da inta lagu jiro ka soo kabashada dhaawaca UV ee unugyada serum-ka laakiin kuma jiraan unugyada iyada oo aan lahayn wax-ka-qabashada serum.Bixinta dibadda ee cytidine ama deoxycytidine waxay fududaysaa dayactirka DNA-da ee ku xiran CMPK ee unugyada serum-ka, taasoo soo jeedinaysa in isku-darka dCDP ama CDP ay go'aamiso heerka dayactirka.Si kastaba ha ahaatee, garaacista CMPK ma saameynayso heerka joogtada ah ee dCTP ee unugyada serum-ka.Waxaan markaa ka helnay meelaynta CMPK ee goobaha waxyeellada DNA-da iyo samaynteeda adag ee Tip60 iyo ribonucleotide reductase.Falanqayntayadu waxay muujisay in N-terminal 32-amino-acid ee CMPK looga baahan yahay qoritaanka goobaha waxyeelada DNA-da ee Tip60-ku-tiirsan.Dib-u-muujinta nooca duurjoogta ah laakiin aan N-terminus la tirtirin CMPK waxay soo celisaa waxtarka dayactirka DNA ee unugyada garaacista CMPK.Waxaan soo jeedinay in samaynta dCDP-ga gaarka ah ee goobta iyada oo loo marayo CMPK ay bixiso hab lagu fududeeyo hagaajinta DNA-da unugyada serum-ka.