Alaabta

Lakabyada burushka polymer-ka ee ku salaysan block copolymers ee poly (oligo (etylene glycol) methacrylate) (POEGMA) iyo poly (glycidyl methacrylate) (PGMA) ayaa lagu sameeyay wafers silikoon by activators ay soo saartay wareejinta elektaroonigga polymerization xagjirka ah (AGET ATRP).Noocyo kala duwan oo biomolecule ah ayaa lagu xidhi karaa lakabyada buraashka iyada oo ay falcelinayaan kooxaha PGMA epoxide ee leh kooxaha amino ee biomolecule, halka POEGMA, oo iska caabisa borotiinka aan khaaska ahayn, ay bixiso jawi ka hortag ah.Dusha sare waxa lagu gartaa xagasha xidhiidhka biyaha, ellipsometry, iyo Fourier transforming infrared spectroscopy (FTIR) si loo xaqiijiyo falcelinta waxka bedelka.Kala soocida wejiga blocks copolymer ee lakabyada waxaa arkay AFM.Saamaynta guryaha dusha sare ee isku xidhka borotiinka ayaa la baadhay iyadoo la adeegsanayo hababka shucaaca.Waxaa la muujiyay in sagxadaha leh lakabyada POEGMA ay ahaayeen kuwo u adkaysta borotiinka, halka tirada borotiinka ee ku xidhan sagxadaha diblock copolymer-ka la beddelay ay korodhay iyadoo korodhay dhumucda lakabka PGMA.Dhaqdhaqaaqa lysozyme ee ku xiran dusha sare waxaa sidoo kale lagu xakameyn karaa iyada oo la beddelo dhumucda lakabka copolymer.Markii biotin lagu daray xannibaadaha copolymer-ka, dusha sare ayaa u adkaystay xayeysiinta borotiinka laakiin waxay muujisay xidhid gaar ah oo avidin ah.Guryahaan, taas oo ah, tirada si fiican loo xakameeyay iyo waxqabadka biomolecules-ka isku xiran iyo gaar ahaan isdhexgalka biomolecules-ka bartilmaameedka ah ayaa laga yaabaa in looga faa'iidaysto hagaajinta saamiga dhawaaqa-ilaa-sanqa ee codsiyada dareemayaasha.Guud ahaan, sagxadaha noocan oo kale ah ayaa laga yaabaa inay faa'iido u yeeshaan sida walxaha aqoonsiga bayooloji ee si gaar ah u sarreeya ee biomaterials shaqeynaya.