4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H) -hal Cas:951-77-9
| Lambarka buugga: | XD90580 |
| Cas: | 951-77-9 |
| Qaanuunka molecular: | C9H13N3O4 |
| Miisaanka Molecular: | 227.22 |
| Helitaanka: | In Stock |
| Qiimo: | |
| Baakad: | 1g USD10 |
| Xidhmo badan: | Codso Xigasho |
Tilmaamaha Alaabta
| Muuqashada | Budada crystalline cad |
| Qiimayn | 99% |
| Meesha dhalaalaysa | 196°C -200°C |
Thymidine phosphorylase (TP, EC 2.4.2.4) waxay aqoonsatay qaab dhismeedka substrate-ka oo leh gaar gaar ah, iyada oo loo sii marayo labada qaybood ee saldhiga iyo ribosyl-ka.Beddelka 3'-OH ee thymidine waxay si muuqata u saamaysay firfircoonideeda firfircoonida TP.Beddelka pyrimidine nucleosides oo leh qaybo saldhig oo wax laga beddelay qaabka 1-fosfate ee u dhigma ayaa ahaa mid liita.Dhaqdhaqaaqa kooxda ka tagay ayaa hoos u dhacay kororka caraf udgoonka unugyada saldhigga pyrimidine, sababtoo ah dhibka sii kordhaya ee salka ku haya acids amino maxaliga ah ee goobta firfircoon.Beddelka kooxaha 3' iyo 5' waxay u janjeersadeen inay hoos u dhigaan heerka falcelinta iyo beddelka boqolkiiba ee TP.Gaar ahaan kooxda ribosyl 3' hydroxyl waxay qaabdhismeed ahaan muhiim u ahayd ku-xidhka substrate-ka ee ensaymku.Qiimaynta kinetic-ku waxay si cad u muujisay K(m) sare iyo qiimayaasha V(max) hooseeya ee lagu bedelayo kooxda 3' hydroxyl ee hydrogen.
