Alaabta

(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran waa iskudhis kiimiko oo ka tirsan fasalka tetrahydrofuran derivatives.Waxaa caadi ahaan loo isticmaalaa berrinkii cilmi-baarista dawooyinka iyo horumarinta sababtoo ah sifooyinka daweynta ee suurtogalka ah.Mid ka mid ah codsiyada muhiimka ah ee xaruntani waxay ku jirtaa awoodda ay u leedahay inay la falgasho noocyo kala duwan oo bayooloji ah, enzymes, ama borotiinnada jidhka bini'aadamka.Is dhexgalkaani wuxuu u horseedi karaa hab-nololeedka dariiqyada biochemical ee gaarka ah, taasoo keeni karta saameyn daweyn.Cilmi-baadhayaashu waxay inta badan sahamiyaan doorka xarunta sida musharaxa daroogada ee suurtogalka ah ee cudurrada kala duwan. Qaababka qaabdhismeedka dhismaha, oo ay ku jiraan joogitaanka giraanta tetrahydrofuran iyo koox phenyl ah oo la beddelay, waxay gacan ka geysataa sifooyinka dawooyinka gaarka ah.Kooxda phenyl waxay bixisaa isdhexgalka hydrophobic, kaas oo laga yaabo inuu saameeyo milanka xarunta iyo isku xirnaanta borotiinnada.Intaa waxaa dheer, joogitaanka atomyada bromine iyo chlorine ee giraanta phenyl waxay ku daraysaa wax-ku-oolnimada fal-celinta kiimikada xarunta, taas oo u oggolaanaysa is-dhexgalka khaaska ah ee molecules bayoolojiga ah ee la beegsanayo. -Bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran si gaar ah reseptors ama ensaymes go'aamin codsiyada daaweynta ee suurtogalka ah.Sidaa awgeed, cilmi-baarayaashu waxay baaraan saamaynta ay ku leeyihiin bartilmaameedyada kala duwan ee molecular, sida reseptors ee ku lug leh caabuqa, kansarka, ama cilladaha habdhiska dhexe ee neerfayaasha. Daraasadaha hore, cilmi-baarayaashu waxay qiimeyn karaan awoodda dhismaha, waxtarka, iyo badbaadada.Qiimaynta bayoolojiga ee kala duwan iyo moodooyinka xayawaanka ayaa la adeegsan karaa si loo go'aamiyo habka ficilka, nuugista, qaybinta, dheef-shiid kiimikaadka, iyo soo saarida.Xogtan ayaa muhiim u ah qiimeynta farmashiyaha xarunta iyo fahamka sida ay ula falgalaan jirka bini'aadamka. Si kastaba ha ahaatee, waxaa muhiim ah in la ogaado in (3S) -3- [4-[(5-Bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran weli waxay ku jirtaa marxaladda cilmi-baarista, iyo codsiyadeeda daaweynta ee suurtagalka ah ayaa weli ah mid si buuxda loo baadho.Daraasado ballaadhan, oo ay ku jiraan tijaabooyinka bukaan-socodka ee bini'aadamka, ayaa lagama maarmaan noqon doona si loo go'aamiyo badbaadada iyo waxtarkeeda ka hor inta aan loo tixgelin isticmaalka daaweynta. Gabagabadii, (3S) -3-[4-[(5-Bromo-2-chlorophenyl) methyl ] phenoxy] tetrahydrofuran ayaa hadda lagu baarayaa codsiyada daweynta ee suurtogalka ah ee cilmi-baarista dawooyinka.Qaab dhismeedkeeda kiimikaad ee gaarka ah waxay gacan ka geysataa isdhexgalka suurtagalka ah ee bartilmaameedyada bayoolojiga ee gaarka ah, furitaanka fursadaha horumarinta wakiilada daweynta cusub.Si kastaba ha ahaatee, cilmi-baaris dheeraad ah iyo qiimeyn ayaa loo baahan yahay si loo go'aamiyo awooddeeda dhabta ah sida xarun daweyn ah.