Alaabta

2-(Chloromethyl) -4-methylquinazoline waa kiimiko kiimiko ah oo ka tirsan qoyska quinazoline.Quinazolines waa isku-dhisyo dabiici ah oo leh qaab-dhismeedka baaskiilka oo ka kooban giraanta benzene oo lagu daray giraanta pyrimidine.Xaruntan gaarka ah waxay haysaa awood la taaban karo oo loogu isticmaalo codsiyada kala duwan, oo ay ku jiraan dawooyinka iyo sayniska agabka. Mid ka mid ah aagga weyn ee 2- (chloromethyl) -4-methylquinazoline ayaa muujisay ballan-qaadka kiimikada daawada.Kala soocida Quinazoline waxay leeyihiin hawlo bayooloji oo kala duwan, taas oo ka dhigaysa inay soo jiidato helitaanka iyo horumarka daroogada.Waxaa lagu baari jiray awooddooda daaweynta cudurro kala duwan, oo ay ku jiraan kansarka, cilladaha neerfaha, iyo cudurrada wadnaha iyo xididdada dhiigga.Cilmi-baarista kansarka, xeryahooda quinazoline-ku-saleysan ayaa soo bandhigay saameynta anti-proliferative iyo anti-buro.Iyagoo joojinaya dariiqyo gaar ah ama borotiinada la beegsaday ee ku lug leh koritaanka unugyada kansarka iyo badbaadada, waxay muujiyeen karti inay yihiin wakiilo daweyn oo macquul ah.Joogitaanka kooxda chloromethyl ee 2- (chloromethyl) -4-methylquinazoline ayaa laga yaabaa inay sii kordhiso waxtarkeeda, maadaama beddelka halogen la muujiyay si loo hagaajiyo bioactivity iyo xulashada daroogooyinka. Enzymes-ka ku lug leh cudurrada neurodegenerative, sida Alzheimers iyo Parkinson.Xeryahooda ayaa muujiyay awoodda ay uga gudbaan xannibaadda dhiigga-maskaxda, iyaga oo si gaar ah u soo jiidanaya bartilmaameedka habka dhexe ee neerfayaasha.Marka laga reebo codsiyadooda dawooyinka, quinazolines waxay sidoo kale heleen isticmaalka sayniska qalabka.Qaab dhismeedkooda molecular ee gaarka ah, oo ay weheliso awoodda ay u leeyihiin in ay ku dhacaan isbeddello kiimikaad oo kala duwan, ayaa ka dhigaya dhismayaal la taaban karo oo loogu talagalay isku dhafka walxaha shaqeynaya.Qalabkani waxa ay soo bandhigi karaan sifooyin ay ka mid yihiin fluorescence, electroconductivity, iyo aqoonsiga molecular, iyaga oo ka dhigaya kuwo waxtar u leh meelaha ay ka midka yihiin optoelectronics, dareenka, iyo catalysis. codsiyada.Fal-celin kiimiko oo kala duwan, sida beddelka, isku-darka, iyo falcelinta isku-xidhka, ayaa la adeegsan karaa si loo soo bandhigo kooxaha shaqeeya ama wax ka beddelka qaab-dhismeedka asaasiga ah.Dabacsanaantani waxay u oggolaanaysaa cilmi-baarayaasha inay naqshadeeyaan oo ay abuuraan derivatives leh sifooyin la xoojiyay ama shaqeynta la beegsanayo. Soo koobid, 2- (chloromethyl) -4-methylquinazoline waa xarun qiimo leh oo leh codsiyada suurtagalka ah ee dawooyinka iyo sayniska alaabta.Nafleydeeda, gaar ahaan kansarka iyo cilmi-baarista neuropharmacology, waxay ka dhigtaa musharax soo jiidasho leh ee horumarinta daroogada.Intaa waxa dheer, qaabdhismeedkeeda kala duwani waxa uu ka dhigayaa dhisme qiimo leh oo loogu talagalay agabka shaqaynaya ee dhinacyada kala duwan.Sida cilmi-baaristu sii socoto, baaritaanno dheeraad ah ayaa daaha ka qaadi doona kartida buuxda iyo ku-dhaqanka xaruntan dhinacyada kala duwan ee sayniska iyo tignoolajiyada.