Alaabta

Streptavidin iyo homologs-keeda (oo si wada jir ah loogu yeero streptavidin) ayaa si weyn loogu isticmaalaa sayniska molecular iyadoo ay ugu wacan tahay isdhexgalka aadka u xulashada iyo isdhexgalka ee biotin.Waxyaabaha kale ayaa sidoo kale gacan ka geysta caannimada nidaamka streptavidin-biotin, oo ay ku jiraan xasilloonida borotiinka iyo hababka biotinylation ee kiimikada iyo enzymatic ee kala duwan ee loo heli karo isticmaalka naqshadaha kala duwan ee tijaabada ah.Tiknoolajiyada ayaa ku riyaaqday dib-u-cusbooneysi nooc ah sanadihii ugu dambeeyay, maadaama noocyo cusub oo streptavidin ah loo sameeyay si ay u buuxiyaan borotiinnada asalka ah iyo hababka cusub ee soo bandhigida biotinylation xulashada ayaa loo sameeyay codsiyada gudaha vitro iyo vivo.Waxaa jiray horumarro la taaban karo oo laga sameeyay dhinacyada catalysis, bayoolaji unugyada, iyo borotokoolka marka lagu daro codsiyada joogtada ah ee meelaha la aasaasay ee ogaanshaha, calaamadaynta iyo gaarsiinta daroogada.Dib-u-eegiddu waxay soo koobaysaa horumarkii ugu dambeeyay ee injineernimada streptavidin iyo codsiyada cusub ee ku salaysan isdhexgalka streptavidin-biotin.