Vancomycin hydrochloride CAS: 1404-93-9 99% Caddaan ama budo casuus ah
Lambarka buugaagta | XD90370 |
Magaca Alaabta | Vancomycin hydrochloride |
CAS | 1404-93-9 |
Qaanuunka molecular | C66H75Cl2N9O24.HCl |
Miisaanka Molecular | 1485.72 |
Faahfaahinta Kaydinta | 2 ilaa 8 °C |
Xeerka Tarifka La Iswaafajiyay | 29419000 |
Tilmaamaha Alaabta
Biyo | NMT 5.0% |
Biraha culus | NMT 30ppm |
pH | 2.5-4.5 |
Bakteeriyada endotoxins | NMT 0.33EU/mg ee Vancomycin |
Cadaynta Xalka | Cad |
Qiimayn | 99% |
Vancomycin B | NLT 900ug/mg |
Xadka monodechlorovancomycin | NMT 4.7% |
Muuqashada | Caddaan, ku dhawaad cad, ama maan ilaa budo casaan ah |
Dhacdooyinka ay bulshadu heshay caabuqa Staphylococcus aureus u adkaysta methicillin waxay ku socotaa xawli naxdin leh.Daawaynta waxtarka leh ayaa taariikh ahaan ku lug lahayd debridement hore iyo maamulka antibiyootiga.Daraasaddan waxaa loo qaabeeyey si loo go'aamiyo waxtarka daaweynta empiric ee daaweynta caabuqyada gacanta.Bukaanka qaba infekshanka gacanta ayaa la siiyay vancomycin xididka empiric marka la seexiyo ama cefazolin xididka ah.Natiijooyinka waxaa lala socday iyadoo la adeegsanayo darnaanta caabuqa, jawaab celinta caafimaad ee habboon, iyo muddada joogitaanka.Waxtarka-kharashka waxaa la xisaabiyay iyadoo la isticmaalayo wadarta kharashka bukaan kasta ee labada kooxood.Falanqaynta tirakoobka ayaa la sameeyay. Afartan iyo lix bukaan ayaa lagu qoray daraasadda.24 ayaa la kala soocay Cefazolin (52.2 boqolkiiba) iyo 22 (47.8 boqolkiiba) vancomycin.Ma jirin farqi xisaabeed oo u dhexeeya kharashka daawaynta (p <0.20) ama celceliska muddada joogitaanka (p <0.18) ee u dhexeeya kooxaha.Bukaannada loo kala soocay cefazolin waxay lahaayeen kharashyo dhexdhexaad ah oo daaweyn ah marka loo eego bukaannada loo kala soocay vancomycin (p <0.05).Bukaanka qaba infekshannada aadka u daran waxay lahaayeen kharashyo daaweyn oo celcelis ahaan qaali ah (p <0.0001) iyo celcelis dheer oo joogitaan (p = 0.0002).Dhammaadkii daraasadda, dhacdooyinka ay bulshadu ka heshay methicillin u adkaysta S. aureus ee cisbitaalka gobolka qorayaasha ayaa la ogaaday inay tahay 72 boqolkiiba, taas oo sababtay in daraasadda ay joojiso wakhti hore guddiga dib u eegista hay'adaha sababtoo ah dhacdooyinka badan Daawaynta ugu horaysa ee ku haboon ee methicillin u adkaysata S. aureus si dhab ah looma dhisin.Ma jiro farqi u dhexeeya natiijada iyadoo la adeegsanayo cefazolin iyo vancomycin sida wakiilka safka hore ayaa la aqoonsaday.