Alaabta

Trifluoromethanesulfonic anhydride, oo caadi ahaan loo yaqaan triflic anhydride ama Tf2O, waa reagent badan oo si weyn loogu isticmaalo isku dhafka dabiiciga ah, gaar ahaan qaybta kimistariga synthetic.Waa xarun firfircoon oo aad u firfircoon oo u adeegta ujeedooyin badan sababtoo ah aysidhka xooggan iyo awoodda ay ku mari karto falcelin kiimiko oo kala duwan. Mid ka mid ah isticmaalka aasaasiga ah ee anhydride triflic waa wakiilka fuuq-baxa.Waxay si xoog leh uga falcelisaa khamriga, iyaga oo u beddelaya ether-kooda u dhigma.Dareen-celintan, oo loo yaqaan 'Williamson ether synthesis', ayaa caadi ahaan looga shaqeeyaa goobaha shaybaadhka iyo hababka warshadaha si loo sameeyo unugyo dabiici ah oo kakan.Triflic anhydride waxay si gaar ah faa'iido u leedahay inay u beddesho khamriga xannibay, kuwaas oo laga yaabo inayan si sahal ah ula falcelin reagents kale, ethers si wax ku ool ah. Intaa waxaa dheer, anhydride triflic waxaa loo isticmaalaa ilaalinta iyo ilaalinta kooxaha shaqeynaya ee iskudhafka organic.Waxa loo isticmaali karaa in lagu ilaaliyo kooxaha hawlaha xasaasiga ah, sida aalkolada iyo aminyada, iyadoo la samaynayo triflates deggan.Triflate-yadan ayaa markaa si door ah loo ilaalin karaa xaaladaha ku habboon si dib loogu soo nooleeyo kooxihii shaqada ee la rabay.Istaraatiijiyadani waxay si gaar ah u qiimo badan tahay isku-dhafka tillaabooyin badan, halkaas oo ilaalinta iyo ka-hortagga kooxaha shaqada ay lagama maarmaan u yihiin si loo gaaro fal-celinta la rabo ee xulashada.Aysiidhkeeda sare, oo ka soo jeeda trifluoromethanesulfonic acid waxay ka dhalisaa joogitaanka biyaha, waxay fududaysaa falcelinta acid-catalyzed.Waxay kor u qaadi kartaa isbeddellada kala duwan sida esterifications, acylations, iyo dib-u-habaynta, taas oo awood u siinaysa isku-dhafka molecules-ka adag. Intaa waxaa dheer, anhydride triflic waxaa loo shaqeeyaa sida korantada xooggan ee falcelinta kala duwan.Waxay la falcelin kartaa nucleophiles si ay u soo bandhigto kooxaha triflyl (CF3SO2), kuwaas oo ah hawlqabadyo kala duwan oo ku jira kiimikada synthetic.Kooxaha Triflyl waxay u dhaqmaan sidii kooxo bixitaan wanaagsan, oo awood u siinaya falcelinta soo socota sida beddelka nucleophilic ama dib-u-habaynta.In kasta oo ay faa'iido leedahay, triflic anhydride waa in si taxadar leh loo maareeyaa sababtoo ah dabeecadeeda aadka u liidata iyo falcelinta suurtagalka ah.Tallaabooyin badbaado oo habboon waa in la qaadaa, oo ay ku jiraan isticmaalka dharka ilaalinta habboon, galoofyada, iyo muraayadaha indhaha, iyo sidoo kale ka shaqaynta meel hawo fiican leh.Marka la soo koobo, triflic anhydride waa reagent qiimo leh oo ku jira isku-darka organic sababtoo ah awooddeeda inuu u shaqeeyo sida wakiilka fuuq-baxa, wakiilka ilaalinta iyo ilaalinta shaqada kooxaha, kicinta, dhiirigeliyaha, iyo electrophile.Kala-duwanaanshaha iyo falcelinta waxay ka dhigaysaa qayb muhiim ah oo ka mid ah hababka shaybaarka badan iyo hababka warshadaha, taas oo awood u siinaysa isku-dhafka hufan ee xeryahooda dabiiciga ah ee kala duwan.Si kastaba ha ahaatee, waa in taxaddar la sameeyaa marka la qabanayo triflic anhydride, u hoggaansanaanta borotokoolka badbaadada saxda ah si loo hubiyo fayoobida farmashiyaha loogana hortago shilalka shaybaarka.