Tazobactam Cas: 89786-04-9
| Lambarka buugaagta | XD92373 |
| Magaca Alaabta | Tazobactam |
| CAS | 89786-04-9 |
| Qaabka molecularla | C10H12N4O5S |
| Miisaanka Molecular | 300.29 |
| Faahfaahinta Kaydinta | -15 ilaa -20 °C |
| Xeerka Tarifka La Iswaafajiyay | 29419000 |
Tilmaamaha Alaabta
| Muuqashada | Caddaan ilaa budo caddaan ah |
| Asay | 99% min |
| Biyo | <0.5% |
| Wareegid gaar ah | +127 ilaa +139 |
| Biraha culus | <20ppm |
| Hadhaaga dabka | <0.1% |
| Wadarta wasakhda | <1.0% |
Tazobactam waa penicillanic acid sulfone oo la mid ah tilmaamaha sulbactam.Waa β-lactamaseinhibitor ka awood badan sulbactam waxayna leedahay hawlo kala duwan oo ka sii ballaadhan marka loo eego clavulanic acid.Waxay leedahay firfircoonida bakteeriyada oo aad daciif u ah.Tazobactam waxay ku jirtaa qiyaas go'an, isku-dubarid la isku duro oo leh piperacillin, penicillin ballaaran oo ka kooban 8: 1 saamiga piperacillin sodium iyo tazobactamsodium miisaan ahaan waxaana lagu suuq geeyaa magaca ganacsiga Zosyn.Labaduba waxay leeyihiin nolol badhkeed oo gaaban (t1/2 1 saac), waa kuwa ugu yar borotiinka, waayo-aragnimada dheef-shiid kiimikaadka oo aad u yar, waxayna ka soo baxaan qaabab aan firfircoonayn oo kaadida ah oo aad u badan.
Tilmaamaha la ansixiyay ee piperacillin-tazobactamcombination waxaa ka mid ah daaweynta appendicitis, postpartumendometritis, iyo cudurrada bararka miskaha ee uu keeno β-lactamase-soo saara E. coli iyo Bacteroides spp., caabuqyada qaab-dhismeedka maqaarka iyo maqaarka oo ay keento β-lactamase-soo saaristaS.aureus, iyo oof-wareen ay keento β-lactamase-soo-saareyaasha hargabka H.
