Alaabta

Si loo baaro cudurka faafa ee unugyada unugyada gonorrhea ee Neisseria gonorrhoeae ee Saskatchewan, Kanada, iyadoo la adeegsanayo Neisseria gonorrhoeae multi antigen typing (NG-MAST), iyo in la qiimeeyo ururada ka dhexeeya u nuglaanta antimicrobial (AMS) iyo noocyo gaar ah oo cadaadis ah (STs). , oo la ururiyey intii u dhaxaysay 2003 iyo 2008, waxaa lagu qoray NG-MAST.ST-yada waa la kooxeeyay haddii mid ka mid ah alleles-kooda uu caadi yahay kan kalena uu ku kala duwan yahay ≤1% habka DNA-da.AMS waxaa lagu go'aamiyay agar dilution (CLSI) ilaa todobo antibiyootik ah. Gonorrheae gonorrheae ayaa lagu xalliyay 82 shaqsi oo NG-MAST STs ah iyo 18 NG-MAST ST kooxo leh kooxo 25, 3655, 921, 3654, 3657 iyo 3656 ka kooban 517.1 /320) ee go'doominta.Gonorrhoeae-ka go'doomin ee u nugul dhammaan dawooyinka jeermiska lidka ku ah ee la tijaabiyey ayaa si weyn (p<0.05) lala xiriiriyay ST 25 (87%).Ururada kale ee muhiimka ah ee u dhexeeya ST iyo AMS waxaa ka mid ah: ST 3654 iyo go'doominta ugu yar ee xakamaynta ≥0.03 mg / L ilaa jiilka saddexaad ee ceph alosporins;ST 3711 (100%) iyo TRNG;iyo ST/koox 3654 (43%) iyo koromosoomyada caabbinta penicillin iyo tetracycline.Dhawr NG-MAST STs/kooxo ayaa si weyn loola xiriiriyay go'doomin leh caabbinta koromosoomyada tetracycline.Go'doominta u adkaysata ciprofloxacin (n=5) iyo azithromycin (n=2) ayaa u muuqday ST-yo gaar ah.Ururada muhiimka ah ayaa lagu arkay shakhsiyaadka ST-yada, jinsiga iyo da'da bukaanka, iyo qaybinta gobolka iyo ku-meel-gaadhka ah.Isbahaysiga u dhexeeya N jabtada AMS iyo NG-MAST STs ayaa la aqoonsaday waxaana laga yaabaa inay faa'iido u yeeshaan saadaasha AMS ee gobol ahaan.Sababtoo ah ST-yada dalal kala duwan ayaa si aad ah u kala duwan, isticmaalka NG-MAST ee saadaasha AMS caalami ahaan waxay u baahan tahay daraasad dheeraad ah.