Alaabta

S-(+)-Methyl-(2-chlorophenyl)[(2- (2-thienyl)amino] acetate hydrochloride, oo sidoo kale loo yaqaan S-(+) -Clopidogrel, waa isku-dar dawo oo leh qaacido kiimiko ah C16H16ClNO2SH·HCl Waa derivative chiral ee clopidogrel, taas oo ah daawo muhiim ah antiplatelet.Isticmaalka aasaasiga ah ee S-(+)-Methyl-(2-chlorophenyl)[(2--thienyl)amino] acetate hydrochloride waa sida firfircoon. Qayb ka mid ah samaynta dawooyinka wadnaha iyo xididdada dhiigga, gaar ahaan wakiilada antiplatelet, waxay bixisaa saameynteeda daweynta iyada oo la xakameynayo isku-darka platelet, ka hortagga sameynta xinjirowga dhiigga, iyo yareynta khatarta dhacdooyinka wadnaha iyo xididdada. Doorka muhiimka ah ee firfircoonida iyo isku-darka platelet-ka.Iyadoo si aan leexleexad lahayn loogu xidhay soo-dhoweeyahan, S-(+)-Methyl-(2-chlorofenyl) [(2--thienyl)amino] acetate hydrochloride waxay joojisaa firfircoonida platelet waxayna ka hortagtaa samaynta xinjirowga dhiigga: Habkan ficilku wuxuu ka dhigayaa dawo lagama maarmaan u ah ka hortagga dhacdooyinka thrombotic ee bukaannada khatarta sare leh, sida kuwa leh taariikhda xanuunka wadnaha ee degdega ah, ischemic stroke, ama cudurada halbowlaha durugsan.S-(+)-Methyl- (2-chlorophenyl) [(2- (2-thienyl)amino] acetate hydrochloride waxaa inta badan lagu maamulaa afka qaab kiniin ama kaabsal ah.Ka dib marka la nuugo, waxay maraysaa beddelaad dheef-shiid kiimikaad ee beerka si ay u dhaliso dheef-shiid kiimikaad firfircoon.Dheef-shiid kiimikaad firfircooni wuxuu si aan leexleexad lahayn ugu xidhaa soo-dhoweeyaha P2Y12, isagoo samaynaya saamayntiisa antiplatelet muddo dheer.Xarunta waxaa sida caadiga ah loo qoraa hal mar maalin kasta, ha ahaato daaweyn gooni ah ama lagu daro daawooyinka kale ee antiplatelet, sida aspirin. Waxaa muhiim ah in la ogaado in S- (+)-Methyl-(2-chlorophenyl)[(2-2-2) -thienyl) amino] acetate hydrochloride waa in loo isticmaalo oo kaliya hagida xirfadlaha daryeelka caafimaadka, sababtoo ah isticmaalkeedu wuxuu yeelan karaa awood.