Niacinamide Cas: 98-92-0
| Lambarka buugaagta | XD91246 |
| Magaca Alaabta | Niacinamide |
| CAS | 98-92-0 |
| Qaabka molecularla | C6H6N2O |
| Miisaanka Molecular | 122.12 |
| Faahfaahinta Kaydinta | Ambient |
| Xeerka Tarifka La Iswaafajiyay | 29362900 |
Tilmaamaha Alaabta
| Muuqashada | Caddaan ama ku dhawaad cad cad budo crystalline ama crystalline aan midab lahayn |
| Asay | ≥99% |
| Meesha dhalaalaysa | 128°C ~ 131°C |
| Aqoonsiga | Wanagsan |
| pH | 6.0 ~ 7.5 |
| Khasaare xagga qallajinta | ≤0.5% |
| Sulfated Ash | ≤0.1% |
| Cadaynta Xalka | Cad |
| Birta culus | ≤0.003% |
| Midabka xalka | ≤BY7 |
Niacinamide sidoo kale loo yaqaan nicotinamide, vitamin B3, ama vitamin PP, waa nooc ka mid ah fiitamiinada biyaha ku milma, waxay ka tirsan yihiin fiitamiinada B, sida coenzyme Ⅰ, nicotinamide adenine dinucleotide (NAD) iyo coenzyme Ⅱ (nicotinamide adenine dinucleotide phosphate, NADP) Qaab-dhismeedka jidhka bini'aadamka labadan nooc ee coenzyme nicotinamide qayb ka mid ah hydrogenation iyo sifooyinka fuuqbaxa ee dib-u-celinta, Waxay ka ciyaartaa doorka gudbinta hydrogen ee biooxidation waxayna kor u qaadi kartaa neefsiga unugyada, habka biooxidation iyo dheef-shiid kiimikaad, taas oo muhiimad weyn u leh ilaalinta sharafta unugyada caadiga ah, gaar ahaan maqaarka, habka dheef-shiidka iyo habdhiska dareenka.Marka la waayo, neefsiga iyo dheef-shiid kiimikaadka unugyada ayaa saameeya waxaana keena pellagra, sidaas darteed alaabtan waxaa inta badan loo isticmaalaa ka hortagga iyo daaweynta pellagra, stomatitis, glossitis iyo wixii la mid ah.
Niacinamide sidoo kale waxaa lagu soo saaraa xayawaanka iyadoo la isticmaalayo niacinamide iyo niacin hoostooda xaaladaha ugu dhawaaqa badan.Pellagra waxay dhacdaa marka jidhku ku yaraado niacin iyo nicotinamide.Markaa waxay ka hortagi karaan pellagra.Waxay door ka ciyaaraan dheef-shiid kiimikaadka borotiinka iyo sonkorta, hagaajinta nafaqada dadka iyo xoolaha.Marka lagu daro daawada, laakiin sidoo kale tiro badan oo cunto iyo cunto lagu daro.Awoodda wax-soo-saarka adduunku waxa ay dhaaftay 30,000 oo tan.Japan, niacinamide waxaa loo isticmaalaa daawada 40% iyo quudinta lagu daro 50%.Waxyaabaha lagu daro cunnada ayaa ah 10%.Nikotinic acid iyo nicotinamide waa kuwo aan sun ahayn oo inta badan ku jira beerka xoolaha, kelyaha, khamiirka iyo sonkorta bariiska ee dhexdhexaadka dabiiciga ah.LD50 ee nicotinamide ee duritaanka maqaarka hoostiisa ee jiirka waxay ahayd 1.7 g/kg.
Isticmaal: dawooyinka fitamiinada, ka qaybqaado habka dheef-shiid kiimikaadka ee jirka, loo isticmaalo ka hortagga iyo daaweynta niacin yaraanta sida pellagra.
Isticmaalka: alaabta daryeelka maqaarka waxay ka hortagi karaan maqaarka qallafsan, ilaalinta caafimaadka unugyada maqaarka, waxay kor u qaadaan caddeynta maqaarka.Loo isticmaalo daryeelka timaha waxay kor u qaadi kartaa wareegga dhiigga madaxa, timaha follicle caafimaad leh, kor u qaadida koritaanka timaha, ka hortagga bidaarta.
Codsiga: Cilmi-baarista biochemical;Halabuurka nafaqeynta dhexdhexaadinta dhaqanka nudaha;Daawooyinka kiliinikada Kiimikada waa koox fitamiin B ah, oo loo isticmaalo ka hortagga iyo daaweynta pellagra, stomatitis, glossia iyo cudurrada kale.
Isticmaal: La mid ah niacin.Biyuhu way ka fiican yihiin niacin, laakiin way fududahay in la sameeyo kakan oo leh fitamiin C iyo agglomerate.Qiyaasta 30-80 mg / kg.
Ujeeddo: Cilmi-baarista biochemical.Dhexdhexaadinta dhaqanka unugyada ayaa la diyaariyey.Warshadaha dawooyinka.
Isticmaal: Aamide oo ka soo jeeda fiitamiin B3 iyo PARP inhibitors.
