Alaabta

N-[(2'-cyano [1,1'biphenyl]-4-yl)methyl]-methyl ester L-valine monohydrochloride waa daawo caadi ahaan loo isticmaalo daawaynta hypertension, sidoo kale loo yaqaan dhiig karka.Waxay ka tirsan tahay fasalka daawooyinka loo yaqaan angiotensin-converting enzyme (ACE) inhibitors. Dhiig karka waa xaalad caadi ah oo kordhin karta khatarta dhibaatooyin caafimaad oo badan, oo ay ku jiraan cudurrada wadnaha, istaroogga, iyo dhaawaca kelyaha.ACE inhibitors, sida N-[(2'-cyano [1,1'biphenyl]-4-yl)methyl]-methyl ester L-valine monohydrochloride, ayaa had iyo jeer loo qoraa si ay u caawiyaan hoos u dhigista cadaadiska dhiigga iyo yaraynta cadaadiska wadnaha iyo Hababka ugu muhiimsan ee ficilka N-[(2'-cyano [1,1'biphenyl]-4-yl)methyl] -methyl ester L-valine monohydrochloride wuxuu xakameynayaa dhaqdhaqaaqa angiotensin-converting enzyme (ACE). ).ACE waxay mas'uul ka tahay inay u beddesho angiotensin I una beddelo angiotensin II, oo ah vasoconstrictor awood leh, kaas oo ciriiriya xididdada dhiigga korna u qaada cadaadiska dhiigga.Iyadoo la xakameynayo ACE, dawadani waxay ka caawisaa ka hortagga samaynta angiotensin II, taasoo keenta vasodilation (balaadhidda xididdada dhiigga) iyo hoos u dhaca cadaadiska dhiigga.N-[(2'-cyano [1,1'biphenyl]-4-yl) )methyl] -methyl ester L-valine monohydrochloride waxaa caadi ahaan afka laga qaataa, inta badan hal mar maalintii.Qiyaasta gaarka ah iyo inta jeer ee maamulka waxay ku xirnaan doontaa arrimo kala duwan, oo ay ku jiraan darnaanta hypertension iyo jawaabta qofka ee daaweynta.Daawadan waxaa laga yaabaa in loo isticmaalo kaligiis ama lagu daro daawooyinka kale ee antihypertensive si loo gaaro xakamaynta cadaadiska dhiigga ugu fiican. Waxaa muhiim ah in la ogaado in N-[(2'-cyano [1,1'biphenyl]-4-yl)methyl]-methyl Ester L-valine monohydrochloride waxay u keeni kartaa waxyeelo gaar ah shaqsiyaadka qaarkood.Dhibaatooyinka caadiga ah waxaa ka mid ah dawakhaad, madax-xanuun, qufac qalalan, iyo daal.Haddii waxyeellooyinkan ay sii jiraan ama ay noqdaan kuwo dhib badan, waxaa lagu talinayaa inaad la tashato xirfadle daryeel caafimaad.Xaalado naadir ah, waxyeellooyin halis ah ayaa dhici kara, sida falcelinta xasaasiyadda, dhibaatooyinka kelyaha, ama anjioedema (barar daran oo wejiga ah, dibnaha, cunaha, ama carrabka).Haddii wax saameyn ah oo daran la kulmo, waa in la raadiyaa daryeel caafimaad oo degdeg ah. Kahor inta aan la bilaabin N-[(2'-cyano[1,1'biphenyl]-4-yl)methyl]-methyl ester L-valine monohydrochloride, waa muhiim. si loo sheego xaalad kasta oo caafimaad ama xasaasiyad dhakhtarka qoray.Daawadu waxa laga yaabaa inaanay ku habboonayn shakhsiyaadka leh taariikhda cudurrada kelyaha, cudurrada beerka, ama cudurrada wadnaha, sababtoo ah waxay ka sii dari kartaa xaaladahan. Soo koobid, N-[(2'-cyano[1,1'biphenyl]-4) -yl)methyl]-methyl ester L-valine monohydrochloride waa ACE inhibitor loo isticmaalo daawaynta hypertension.Iyadoo la xakameynayo ACE, waxay caawisaa inay ballaariso xididdada dhiigga iyo hoos u dhigista cadaadiska dhiigga.U hoggaansanaanta qiyaasaha la qoray, dabagal joogto ah oo lala yeesho xirfadlayaasha daryeelka caafimaadka, iyo la socodka waxyeellooyinka iman kara ayaa muhiim u ah isticmaalka badbaadada iyo waxtarka leh ee dawadan.Waxa kale oo muhiim ah in la ilaaliyo qaab nololeed caafimaad leh, oo ay ku jiraan jimicsi joogto ah, cunto isku dheeli tiran, iyo maareynta cadaadiska, si loo sii taageero xakamaynta cadaadiska dhiigga.