Metronidazole Cas: 443-48-1
| Lambarka buugaagta | XD91888 |
| Magaca Alaabta | Metronidazole |
| CAS | 443-48-1 |
| Qaabka molecularla | C6H9N3O3 |
| Miisaanka Molecular | 171.15 |
| Faahfaahinta Kaydinta | 2-8°C |
| Xeerka Tarifka La Iswaafajiyay | 29332990 |
Tilmaamaha Alaabta
| Muuqashada | Budada crystalline cad |
| Asay | 99% min |
| barta dhalaalaysa | 159-161 °C (Iftiin) |
| Barta karkarinta | 301.12°C (qiyaasta qallafsan) |
| cufnaanta | 1.3994 (qiyaas aan caadi ahayn) |
| index refractive | 1.5800 (qiyaas) |
| Fp | 9℃ |
| milmayn | acetic acid: 0.1 M, cad, huruud daciif ah |
| pka | pKa 2.62(H2O,t =25±0.2, aan la qeexin) |
| Biyo La'aanta | <0.1 g/100 ml at 20ºC |
Metronidazole waa daawada doorashada ee amebiases, trichomonasis siilka iyo trichlomonadic urethritis ee ragga, lambliosis, amebic dysentery, iyo infekshannada anaerobic ee ay keenaan sheyga u nugul daroogada.Ereyada la midka ah ee dawadan waa flagyl, protostat, trichopol, iyo vagimid.
Metronidazole waxaa loo heli karaa sida afka, siilka, jirka la mariyo, iyo diyaarinta parenteral.Waxaa soo saaray shirkado dhowr ah, laakiin kaliya waxaa lagu heli karaa warqad dhakhtar.Soo-gaadhista deegaanka ee aan ula kac ahayn lagama yaabo, haddii ay dhacdona, uma badna inay keento suntan.
Waxa loo isticmaalaa sidii jeermiska bakteeriyada daawaynta rosacea.Antiprotozoal (trichomonas).Kansarka aadanaha oo suurtagal ah.
Metronidazole, waa antibiyootiko iyo wakiilka antiprotozoal.Waxaa inta badan loo isticmaalaa in lagu daaweeyo ama looga hortago caabuqyada habdhiska ama maxaliga ah ee ay keento bakteeriyada anaerobic, sida caabuqa bakteeriyada anaerobic ee ku jira daloolka caloosha, habka dheef-shiidka, habka taranka haweenka, habka neefsashada hoose, maqaarka iyo unugyada jilicsan, lafaha iyo kala-goysyada, iwm. , caabuqa meningeal, iyo colitis oo ay keento isticmaalka antibiyootiga ayaa sidoo kale waxtar leh.Teetanaha waxaa badanaa lagu daaweeyaa teetanada antitoxin (TAT).Waxa kale oo loo isticmaali karaa infekshanka anaerobic ee afka.Oktoobar 27, 2017, liiska kansarka ee ay daabacday Hay'adda Caalamiga ah ee Caafimaadka Adduunka ee Cilmi-baarista Kansarka ayaa si hordhac ah loo soocay si loo tixraaco, metronidazole ayaa lagu daray liiska 2B kansarka.Bishii Janaayo 2020, metronidazole waxaa loo doortay dufcaddii labaad ee liiska iibka dawooyinka dhexe ee qaranka.
Metronidazole waa wakiilka ugu waxtarka badan ee loo heli karo daaweynta shakhsiyaadka leh dhammaan noocyada amebiasis, laga yaabee marka laga reebo qofka asymptomatic-ka ah laakiin sii wada inuu sii daayo fiix.Xaaladdaasi waxay u baahan tahay amebicide intraluminal waxtar leh, sida furoate diloxanide, paromomycin sulfate, ama diodohydroxyquin.Metronidazole waxay ka hortagtaa fiix xiidmaha iyo xiidmaha ka baxsan iyo trophozoites.
Inkasta oo quinacrine hydrochloride loo isticmaalay daawaynta giardiasis, dhakhaatiir badan ayaa door bida metronidazole.Furazolidone waa doorasho kale.
Metronidazole waa daawada doorashada ee Yurub ee caabuqyada bakteeriyada anaerobic;welwelka laga qabo kansarka suurtagalka ah ee kansarka ayaa horseeday taxaddar isticmaalka gudaha Mareykanka. Dhawaan waxaa la ogaaday inay waxtar u leedahay daaweynta cudurrada D. medinensis (Guinea worm) iyo Helicobacter pylori.
Waxa kale oo loo isticmaalaa finanka rosacea, balantidiasis iyo caabuqa gooryaanka Guinea.T. Caabuqyada siilka ee u adkaysta qiyaasta caadiga ah waxay u baahan yihiin daaweyn gaar ah.
