Iodonitrotetrazolium chloride CAS: 146-68-9
Lambarka buugaagta | XD90473 |
Magaca Alaabta | Iodonitrotetrazolium chloride |
CAS | 146-68-9 |
Qaanuunka molecular | C19H13ClIN5O2 |
Miisaanka Molecular | 505.70 |
Faahfaahinta Kaydinta | 2 ilaa 8 °C |
Xeerka Tarifka La Iswaafajiyay | 32129000 |
Tilmaamaha Alaabta
Aqoonsiga | H-NMR |
Muuqashada | Jaale fudud ilaa budo liimi ah |
Qiimayn | >99% |
Solubility | xal cad |
Interferon-induced transmembrane protein 1 (IFITM1) waa mid ka mid ah xubnaha qoyska borotiinka transmembrane interferon.Daraasaddan, waxaan ku soo sheegnay in kor u kaca IFITM1 ee kansarka mindhicirka ee bini'aadamka (CRC) ay si weyn ula xiriirto CRC lymph node iyo masaafada fogaanta iyo sidoo kale marxalad caafimaad oo horumarsan.Muhiimad ahaan, kor u qaadida IFITM1 muujinta waa arin saadaasha madax banaan ee badbaadada liidata.Si loo baaro hababka molecular, waxaan tusnay in muujinta xad-dhaafka ah ee IFITM1 ee unugyada CRC la dalacsiiyay, halka garaaca IFITM1 muujinta la joojiyay, guuritaanka unugyada / duulaanka iyo tumorigenicity in vitro.Intaa waxaa dheer, waxaan u aqoonsanay Caveolin-1 (CAV1) sida bartilmaameedka hoose ee IFITM1-ku-soo-soo-kabashada unugga, sida garaacista CAV1 la tirtiray siIFITM1 dhexdhexaadin ka-hortagga duulaanka unugyada unugyada CRC.Intaa waxaa dheer, kooxda CRC ee bukaannada 229, muujinta IFITM1 waxay la xiriirtaa muujinta CAV1.Natiijooyinkani waxay soo jeediyeen in IFITM1 ay kor u qaaddo dareenka xun ee unugyada CRC, waana calaamad saadaal ah oo suurtagal ah iyo bartilmaameedka daaweynta ee CRC.