Carbenicillin disodium cusbo CAS:4800-94-6 Caddaan ilaa budo cad ah
Lambarka buugaagta | XD90371 |
Magaca Alaabta | Carbenicillin disodium cusbo |
CAS | 4800-94-6 |
Qaanuunka molecular | C17H16N2Na2O6S |
Miisaanka Molecular | 422.36 |
Faahfaahinta Kaydinta | 2 ilaa 8 °C |
Xeerka Tarifka La Iswaafajiyay | 29411000 |
Tilmaamaha Alaabta
pH | 5.5-7.5 |
Waxyaalaha biyaha | ≤ 6.0% |
Solubility | Xal cad oo huruud ah oo yar |
Qiimayn | 99% |
Awoodda | 830ug/mg |
Pyrogens | ≤ 80mg/kg |
Gudbinta | U hogaansama |
Muuqashada | Caddaan ilaa budo caddaan ah |
Walxaha Iodine Nuugista | ≤ 8.0% |
Heerka Usp | U hogaansama |
Assay (penicillin G) | U hogaansama |
Cystic fibrosis waa cillad hidde-side ah kaas oo xabka aan caadiga ahayn ee sambabada uu la xiriiro u nuglaanta caabuqa joogtada ah.Ka-darka sambabada waa marka calaamadaha caabuqa ay noqdaan kuwo aad u daran.Antibiyootigyada waa qayb muhiim ah oo ka mid ah daawaynta ka sii daraysa iyo antibiyootiga la nuugo waxa la isticmaali karaa kaligii ama iyadoo lala kaashanayo antibiyootiga afka si ay uga sii darto antibiyootiga xididada ee caabuqyada daran.Antibiyootikada la nuugo ma keento saameyn xun oo la mid ah antibiyootigyada xididada waxaana laga yaabaa inay caddeyso beddelka dadka ay si xun u heli karaan xididadooda. dugsiga ama shaqada oo waxay wanaajisaa badbaadadooda muddada dheer. Waxaan ka baadhnay ClinicalTrials.gov iyo Diiwaanka Tijaabada Caafimaad ee Australia iyo New Zealand si loo helo tijaabooyin la xidhiidha.Taariikhdii raadinta u dambeysay: 15 March 2012 Waxaan sidoo kale baadhnay Diiwaanka Tijaabooyinka Cystic Fibrosis ee Cochrane Cystic Fibrosis G roup.Taariikhda raadinta ugu dambeysa: 01 Juun 2012. Tijaabooyin aan kala sooc lahayn oo la xakameeyey oo lagu sameeyay dadka qaba cystic fibrosis oo leh sambabada sambabada oo daawaynta antibiyootiga la neefsado ayaa la barbardhigay placebo, daawaynta caadiga ah ama antibiyootig kale oo la neefsado inta u dhaxaysa hal ilaa afar toddobaad. Laba dib-u-eegis qorayaasha si madaxbannaan tijaabooyin la doortay, oo la qiimeeyay halista eexda ee tijaabo kasta iyo xogta la soo saaray.Qorayaasha tijaabooyinka lagu daray ayaa lala xiriiriyay macluumaad dheeri ah.Lix tijaabo oo kaqeybgalayaasha 208 ayaa lagu daray dib u eegista.Tijaabooyinku way kala duwanaayeen qaabaynta iyo dhex galka (si kastaba ha ahaatee, dhammaan waxa ku jiray tijaabooyin marka la barbar dhigo dawooyinka antibiyootiga ee la nuugo ee xididada laga qaado).Khatarta eexda way adkeyd in la qiimeeyo inta badan tijaabooyinka.Natiijooyinka si buuxda looma sheegin oo xog xaddidan oo keliya ayaa loo heli karaa falanqaynta.Afar tijaabo ayaa soo sheegay qaar ka mid ah natiijooyinka mugga qasabka ah ee lagu qasbay hal ilbiriqsi mana helin farqi weyn oo u dhexeeya antibiyootiga la neefsado iyo faragelinta wiilka isbarbardhigga ah.Laba ka mid ah tijaabooyinkan oo la isticmaalayo 300 mg oo tobramycin ah oo la nuugo, isbeddelka mugga dhicis ee qasabka ah ee hal ilbiriqsi wuxuu la mid yahay tobramycin xididada;iyo hal tijaabo waqtiga ilaa ka sii daraynta xiga ma kala duwanayn.Wax saameyn xun oo muhiim ah lama soo sheegin. Waxaa jira wax yar oo faa'iido leh oo caddayn heer sare ah oo lagu qiimeeyo waxtarka antibiyootiga la nuugo ee daaweynta sii xumeynta sambabada ee dadka qaba cystic fibrosis.Tijaabooyinkii lagu soo daray ma ahayn kuwo awood ku filan leh si ay u gaaraan yoolalkooda.Sidaa awgeed, ma awoodno inaan muujino in mid ka mid ah daawaynta uu ka sareeyo kan kale iyo in kale.Cilmi-baaris dheeraad ah ayaa loo baahan yahay si loo ogaado in tobramycin la neefsado loo isticmaali karo beddelka tobramycin-ka-xididdada ee qaar ka mid ah sii-daridda sambabada.