Alaabta

Benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride waa iskudar kiimiko oo leh codsiyo suurtagal ah oo ku saabsan daawada iyo cilmi baarista dawooyinka.Waxay ka kooban tahay koox benzyl ah oo ku xiran shaqeynta carbamate, taas oo iyana ku xiran unugyada hexahydro-1H-pyrrolizin-7a-ylmethyl.Ku darida hydrochloride ee xarunta waxay muujinaysaa joogitaanka chloride ion, kaas oo kor u qaadaya milmigiisa biyaha.Carbamates, guud ahaan, waxaa loo yaqaanaa inay soo bandhigaan dhaqdhaqaaqyo bayooloji oo kala duwan, oo ay ku jiraan anticonvulsant, kansarka ka hortagga, iyo guryaha antihypertensive.Joogitaanka kooxda benzyl ee benzyl N- ({hexahydro-1H-pyrrolizin-7a-yl}methyl) karbamate hydrochloride waxay bixin kartaa lipophilicity la hagaajiyay, taasoo u oggolaanaysa inay si fudud uga gudubto xuubabka gacanta.Tani waxay faa'iido u yeelan kartaa bixinta daroogada iyo hagaajinta bioavailability. Hexahydro-1H-pyrrolizin-7a-ylmethyl moiety, oo sidoo kale loo yaqaan 'piperidinyl moiety', ayaa caadi ahaan laga helaa xeryahooda bioactive.Piperidines waxaa loo yaqaanaa doorkooda sida inhibitors enzyme, modulators neurotransmitter, iyo wakiilada anti-bararka.Ku darista qaybtan xarunta waxay kor u qaadi kartaa dhaqdhaqaaqa bayoolojiga iyo kartida daweynta.In kasta oo la'aanta macluumaad gaar ah oo ku saabsan isticmaalka tijaabada ama kiliinikada ee xarunta, codsiyada suurtagalka ah ayaa la qiyaasi karaa iyadoo lagu saleynayo sifooyinka la yaqaan ee kooxaha ka kooban.Benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl)carbamate hydrochloride waxaa laga yaabaa in loo sahamiyo sidii musharraxa daroogada ee xaaladaha sida suuxdin, kansarka, dhiig-karka, ama xanuunada neurodegenerative.Waxa kale oo loo isticmaali karaa sidii dhisme ama dhexdhexaad ah isku-dhafka xeryahooda kale ee bioactive. Waxaa muhiim ah in la ogaado in ka hor codsi kasta oo la taaban karo ama baaritaan dheeraad ah, cilmi-baaris qotodheer iyo tijaabo oo ay ku jiraan daraasadaha sunta ah, kobcinta kimistariga daawada, iyo qiimeynta bartilmaameedyada gaarka ah. waa in la qabtaa.Tani waxay gacan ka geysan doontaa go'aaminta badbaadada, waxtarka, iyo habka saxda ah ee ficilka benzyl N-({hexahydro-1H-pyrrolizin-7a-yl}methyl) hydrochloride karbamate, ugu dambeyntiina u horseedaysa ka faa'iidaysiga suurtagalka ah ee goobta caafimaadka.