Azure B, CAS la xaqiijiyay: 531-55-5 Budada cagaaran ee madow
Lambarka buugaagta | XD90500 |
Magaca Alaabta | Azure B, shahaado |
CAS | 531-55-5 |
Qaanuunka molecular | C15H16ClN3S |
Miisaanka Molecular | 305.83 |
Faahfaahinta Kaydinta | Ambient |
Xeerka Tarifka La Iswaafajiyay | 32129000 |
Tilmaamaha Alaabta
Muuqashada | Budada cagaaran ee madow |
Qiimayn | 99% |
Cayilka, nooca 2-aad ee sonkorowga iyo hyperlipidemia ayaa si joogta ah u wada nool waxaana lala xiriiriyaa kororka cudurrada iyo dhimashada.Isticmaalka karbohaydrayt la safeeyey iyo gaar ahaan fructose ayaa si aad ah u kordhay sannadihii u dambeeyay waxana ay barbar-dhigtay dhacdooyinka korodhka buurnaanta iyo macaanka.Daraasadaha dadka iyo xayawaanku waxay muujiyeen in qaadashada fructose ee cuntada sare ay si togan ula xiriirto kororka dyslipidemia, caabbinta insulin, iyo hypertension.Dheef-shiid kiimikaad ee fructose waxay ku dhacdaa ugu horrayn beerka iyo qulqulka fructose ee sarreeya waxay keenaysaa kor u qaadista triglyceride beerka (hepatic steatosis).Tani waxay keentaa gulukoos iyo dheef-shiid kiimikaad lipid iyo kor u kaca muujinta cytokine ee bararka.Halkan waxaan ku muujineynaa in fructose ay beddesho muujinta kicinta gulukooska ee Acetyl CoA carboxylase (ACC), pSer hormoonka xasaasiga ah lipase (pSerHSL) iyo adipose triglyceride lipase (ATGL) ee hepatic HepG2 ama dhaqamada unugyada hepatic ee aasaasiga ah ee vitro.Tani waxay la xidhiidhay kororka de novo triglyceride synthesis in vitro iyo steatosis hepatic in vivo ee fructose-ka-hortagga gulukooska-quudinka iyo jiirarka quudinta caadiga ah.Daraasadahaani waxay bixiyaan aragti cusub oo ku saabsan hababka ku lug leh fructose-dhexdhexaadinta hypertriglyceridemia hepatic hypertriglyceridemia waxayna aqoonsadaan fructose-qaadista inay tahay bartilmaameed cusub oo daaweyn ah oo loogu talagalay cudurrada la xiriira lipid.