Alaabta

Biofilimyadu waxay ka kooban yihiin unugyo bakteeriyayaal ah oo ku dhex jira matrix polymeric ah oo ka baxsan unugga.Poly-beta(1,6)-N-acetyl-d-glucosamine (PNAG) waa qayb ka mid ah matrix biofilm-ka weyn ee bakteeriyada phylogenetically kala duwan.Daraasaddan waxaan ku baarnay sifooyinka jireed iyo kiimikaad ee matrix PNAG ee biofilms oo ay soo saartay in vitro ay soo saartay gram-negative porcine pathogene neef-mareenka Actinobacillus pleuropneumoniae iyo aaladda garaam-positive-ga ee ku xiran bakteeriyada Staphylococcus epidermidis.Saamaynta PNAG ee qulqulka dareeraha bulk waxaa lagu go'aamiyay iyadoo la cabbirayo heerka isu-soo-baxa dareeraha iyada oo loo marayo biofilms oo lagu beeray aaladaha filter-ka-centrifugal.Heerka isku dhufashada dareeraha ayaa si aad ah uga sarreeyay biofilms-ka lagu dhaqmo iyadoo ay jirto PNAG-degrading enzyme dispersin B marka loo eego biofilms-ka la dhaqay iyada oo aan lahayn ensaymka, taas oo muujinaysa in PNAG ay hoos u dhigto socodka dareeraha badan.PNAG waxa kale oo ay xannibtay gaadiidkii quaternary ammonium compound cetylpyridinium chloride (CPC) iyada oo loo marayo biofilms.Ku-xidhka CPC ee fiilooyinka biofilm-yada ayaa sii xannibay isu-soo-baxa dareeraha iyo xannibaadda gaadiidka dheeha azo Allura cas.Bioactive CPC ayaa si hufan looga soo saaray biofilms iyadoo lagu daawaynayay 1 M sodium chloride.Isku soo wada duuboo, natiijooyinkani waxay soo jeedinayaan in CPC ay si toos ah uga falceliso shaxanka PNAG oo ay bedesho sifooyinka jidheed iyo kiimikaad.Natiijooyinkayagu waxay muujinayaan in PNAG ay door muhiim ah ka ciyaarto xakamaynta xaaladda jireed ee biofilms waxayna ka qayb qaadan kartaa hababka dheeraadka ah ee biofilm-ku xiran sida iska caabbinta biocide.