Alaabta

5- (Bromomethyl) -4- (4-fluorophenyl) -6-isopropyl-2-[methyl (methylsulfonyl) amino] pyrimidine waa unug kiimiko ah oo ka hela isticmaalka cilmi-baarisyo kala duwan, dawooyinka, iyo codsiyada warshadaha.Xaruntan waxaa loo yaqaanaa dabeecadeeda kala duwan iyo awoodda ay u leedahay horumarinta molecules iyo daroogooyinka gaarka ah sababtoo ah qaab-dhismeedkeeda gaarka ah iyo kooxaha falcelinta. daroogooyinka.Joogitaanka atom bromine, atom fluorine, kooxda isopropyl, iyo qaab dhismeedka giraanta pyrimidine waxay ka dhigaysaa dhisme soo jiidasho leh oo abuuraya unugyo cusub oo leh hanti la doonayo.Chemists iyo cilmi-baarayaasha dawooyinka ayaa wax ka beddeli kara oo shaqeyn kara xaruntan si ay u soo bandhigaan waxqabadyo gaar ah ama qaab dhismeed kuwaas oo faa'iido u leh ficilka daroogada ee la beegsanayo ama la xoojiyay guryaha farmashiyaha. Intaa waxaa dheer, joogitaanka kooxaha methyl iyo methylsulfonyl ee xaruntu waxay ka dhigtaa mid faa'iido leh ee isku-dhafka organic.Kooxda methylsulfonyl waxay la kulmi karaan falcelino kala duwan, sida barokaca nucleophilic, baabi'inta, ama oksaydhka, taas oo u oggolaanaysa soo bandhigida kooxo kala duwan oo shaqeynaya molecule bartilmaameedka.Kala duwanaanshiyahani wuxuu ka dhigayaa mid qiimo leh abuurista xeryahooda organic adag ee goobta shaybaarka. Intaa waxaa dheer, qaab-dhismeedka xaruntu waxay ka dhigaysaa mid faa'iido u leh daraasadaha cilmi-baarista.Atamka fluorine-ka iyo qaar kale oo baddal ah ayaa laga yaabaa inay gacan ka geystaan ​​dhismaha gaarka ah ee jireed ama kiimikaad, taasoo ka dhigaysa mid ku habboon baaritaanka dhacdooyinka qaarkood ama xarun tixraac ah oo daraasado isbarbardhig ah.Cilmi-baadhayaashu waxay inta badan isticmaalaan xeryahooda sida si ay u fahmaan isdhexgalka noolaha, barashada kinetics falcelinta, horumarinta hababka cusub ee synthetic, ama kor loogu qaado waxqabadka hababka warshadaha ee jira. Waxaa muhiim ah in la ogaado in isticmaalka gaarka ah iyo codsiyada suurtagalka ah ee 5- (Bromomethyl) -4- ( 4-fluorophenyl) -6-isopropyl-2-[methyl (methylsulfonyl) amino] pyrimidine way kala duwanaan kartaa iyadoo ku xiran qaybta gaarka ah ee cilmi baarista ama warshadaha.Codsiyada suurtagalka ah ee xaruntu waxay ka badan yihiin kuwa hore loo sheegay, faa'iidooyinkeedana waxaa laga yaabaa inay sahamiyaan farmashiistaha, farmashiyeyaasha, biochemists, iyo saynisyahano kale oo ku lug leh baaritaanka daroogada, sayniska maadada, ama cilmi-baarista molecular. Soo koobid, 5-(Bromomethyl) -4 -(4-fluorophenyl) -6-isopropyl-2-[methyl (methylsulfonyl) amino] pyrimidine waa isku-dhismeed isku-dhafan oo haya ballan-qaadka cilmi-baarista dawooyinka, kiimikada, iyo warshadaha.Qaab dhismeedkeeda gaarka ah iyo kooxaha falcelinta waxay ka dhigaan dhisme soo jiidasho leh oo loogu talagalay soo saarista unugyada cusub ee daroogada iyo baaritaanka falcelinta kiimikaad ee kala duwan.Codsiyada suurtagalka ah ee xaruntu waa ballaaran yihiin, sahaminta dheeraadka ah ee hantideeda ayaa laga yaabaa inay u gogol xaarto horumarka laga gaaray dhinacyo badan oo saynis ah.