Alaabta

4-Chlorophenylboronic acid waa iskudhis dabiici ah oo ka hela codsi ballaadhan dhinacyo kala duwan, oo ay ku jiraan isku-darka organic, kimistariga, iyo sayniska agabka.Waxay ka kooban tahay giraan phenyl ah oo lagu beddelay kooxda chloro (-Cl) iyo kooxda boronic acid (-B (OH) 2) .Mid ka mid ah isticmaalka aasaasiga ah ee 4-Chlorophenylboronic acid waa doorkeeda sida reagent qiimo leh ee palladium-catalyzed. falcelinta isku-tallaabta, sida Suzuki-Miyaura iyo falcelinta Heck.Dareen-celintani waxay ku lug leedahay samaynta curaarta kaarboon-carbon, halkaas oo 4-Chlorophenylboronic acid u dhaqmo sida il boron ah oo ku lammaansan kara electrophiles kala duwan, sida aryl ama vinyl halides.Tani waxay awood u siinaysaa isku-darka xeryahooda dabiiciga ah ee kala duwan, oo ay ku jiraan daawooyinka, agrochemicals, iyo alaabta. Intaa waxaa dheer, 4-Chlorophenylboronic acid waxaa lagu sii hagaajin karaa kiimiko si loo soo bandhigo kooxo shaqo oo dheeraad ah.Tusaale ahaan, waxay mari kartaa falcelin amination si ay u sameeyaan 4-chloro-phenylboronates, taas oo noqon karta dhexdhexaadiye waxtar u leh isku dhafka kala duwan ee nitrogen-ka kooban.Kala duwanaanta kooxdan shaqaynaysa waxay kor u qaadaysaa isticmaalka synthetic ee 4-Chlorophenylboronic acid, taas oo u oggolaanaysa abuurista molecules adag oo leh sifooyin gaar ah. Codsiga kale ee muhiimka ah ee 4-Chlorophenylboronic acid wuxuu ku jiraa kiimikada daawada.Waxay muujisay ballan farmacophore ahaan ama xannibaad dhisme oo loogu talagalay horumarinta isku-dhisyada noolaha.Sababtoo ah unugyada boronate, 4-Chlorophenylboronic acid waxay samayn kartaa curaarta kondhomka ah ee dib loo rogi karo oo leh molecules ka kooban diol, sida karbohaydraytyada iyo nucleotide.Is dhexgalkaan waxaa loo adeegsaday si loo naqshadeeyo inhibitors enzyme, ligands reseptor, iyo wakiilada kale ee dawooyinka.Tusaale ahaan, inhibitors-ku-salaysan boron-ku-salaysan borotiinka ayaa loo sameeyay daaweynta myeloma badan. Dhinaca sayniska qalabka, 4-Chlorophenylboronic acid waxay heshay codsi ku saabsan wax ka beddelka dusha sare ama isku-darka qalabka shaqada.Adigoo ka faa'iideysanaya kooxda boronic acid, waxay sameyn kartaa dhismo dib loo rogi karo oo xooggan oo leh polyols ama xeryahooda ka kooban hydroxyl.Hantidan waxaa looga faa'iidaysan karaa shaqeynta dusha sare, sida abuurista dahaarka kicinta kicinta ama diyaarinta dareemayaasha si loo ogaado karbohaydraytyada ama falanqaynta kale , iyo cilmiga qalabka.Falcelinteeda samaynta curaarta kaarboon-carbon, awoodda hordhaca kooxeed shaqaynaysa, iyo awoodda samaynta curaarta covalent dib loo rogi karo ayaa ka dhigaysa qalab muhiim u ah cilmi-baarayaasha qaybaha sayniska ee kala duwan.