Alaabta

4-Carboxyphenylboronic acid waa iskudhis organic ah oo ka tirsan qoyska boronic acids.Qaab dhismeedkeeda kiimikaad waxa uu ka kooban yahay atom boron oo ku xidhan kooxda karboksyphenyl.Xaruntani waxa ay heshay codsiyo badan oo dhinacyo kala duwan ah sida synthesis organic, sayniska agabka, kimistari daawaynta, iyo catalysis.One ka mid ah codsiyada muhiimka ah ee 4-Carboxyphenylboronic acid waa in aagga isku-dhafka organic.Waxa caadi ahaan loo adeegsadaa falcelinta isku-xidhka palladium-catalyzed, gaar ahaan Suzuki-Miyaura iyo falcelinta isku-xidhka Chan-Lam.Ka qaybqaadashada ilaha boron ahaan, waxay samayn kartaa curaarta kaarboon-kaarboon ee leh substrates organic, sida aryl ama vinyl halides.Tani waxay u ogolaanaysaa farmashiyeyaashu inay dhisaan unugyo dabiici ah oo adag iyo xeryahooda si hufan u shaqeeya.Awoodda lagu soo bandhigo kooxda karboksyphenyl waxay ku siinaysaa wax-ka-beddelka iyo habeynta sifooyinka xayndaabyada ka dhashaWaxay awood u siinaysaa soo bandhigida unugyada boronic acid, taas oo bixisa sifooyin gaar ah iyo falcelinta xeryahooda bartilmaameedka ah.Tusaale ahaan, asiidhyada boronic waxay u dhaqmi karaan sidii horjoogayaasha protease-ka, iyo marka lagu daro kooxda karboksyphenylboronic acid, cilmi-baarayaashu waxay awood u leeyihiin inay wax ka beddelaan dhaqdhaqaaqa enzyme ama naqshadeeyaan xannibaado gaar ah oo enzyme-ku-talagal ah.Intaa waxaa dheer, joogitaanka kooxda karboksilic acid waxay awood u siinaysaa xarunta si ay u sameeyaan bonds hydrogen oo leh biomolecules, kor u qaadida xiriirka ay u leedahay soo-dhoweynta borotiinka, sidaas darteed saameyn ku yeelanaya dhaqdhaqaaqooda bayooloji. xirmooyinka leh polyols ama iskudhisyo ka kooban hydroxyl.Gurigan wuxuu u oggolaanayaa in loogu shaqeeyo sidii qayb ka mid ah isku-darka agabyada horumarsan sida hydrogels, bioconjugates, ama polymers-ka-celinta kicinta.Iyada oo lagu darayo 4-Carboxyphenylboronic acid walxahan, hantidooda waa la habeyn karaa, taas oo u oggolaanaysa codsiyada sida hababka gudbinta daroogada, dareemayaasha, iyo qalabka casriga ah. Intaa waxaa dheer, kooxda karboxyphenylboronic acid ee xaruntan waxay awood u siineysaa inay u dhaqmaan sidii kicinta falcelino dhowr ah. .Waxay ka qaybqaadan kartaa kicinta aashitada-saldhigga, ka-saarista, iyo falcelinta dareen-celinta.Dhaqdhaqaaqa catalytic-ka ah waxaa looga faa'iidaysan karaa isku-darka dawooyinka, kiimikooyinka wanaagsan, iyo molecules kale ee organic. Gebogebadii, 4-Carboxyphenylboronic acid waa iskudhis isku dhafan oo ka hela faa'iidada qaybaha sayniska ee kala duwan.Codsiyadeedu waxay u dhexeeyaan isku-dhafka dabiiciga ah iyo kimistariga daawaynta ilaa agabka sayniska iyo catalysis.Awooddeeda ka qayb qaadashada falcelinta isku-dhafan ee palladium-catalyzed, awooddeeda sida dhismaha dhismaha xeryahooda firfircoon ee noolaha, iyo doorkeeda kicinta waxay ka dhigtaa qalab lagama maarmaan u ah cilmi-baarayaasha raadinta horumarinta aqoonta iyo horumarinta xalal cusub.