Alaabta

3-tert-Butoxycarbonylphenylboronic acid, sidoo kale loo yaqaan Boc-phenylboronic acid, waa derivative boronic muhiim ah oo leh codsiyo muhiim ah in synthesis organic iyo kimistari. isku duubni.Kooxda tert-butyloxycarbonyl (BOC) ayaa caadi ahaan loo shaqeeyaa si ay si ku meel gaar ah u ilaaliyaan kooxaha shaqada aminiga ah inta lagu jiro falcelino kala duwan.Marka lagu lifaaqo kooxda BOC ee qaybta amiinada, falcelinta amiinka waa la dhimay, taas oo u oggolaanaysa falcelinta xulashada ee boosaska kale ee molecule-ka.Kooxda BOC si fudud ayaa looga saari karaa xaalado khafiif ah, sidaas awgeed waxay daaha ka qaadaysaa shaqada aminiga ee asalka ah.Istaraatiijiyadan kooxda ilaalinta waxay awood u siinaysaa isku-dubarid hufan oo ah unugyo dabiici ah oo kakan, sida dawooyinka iyo alaabada dabiiciga ah. Intaa waxa dheer, 3-tert-Butoxycarbonylphenylboronic acid waxay u adeegtaa sidii reagent qiimo leh samaynta curaarta carbon-carbon.Asiidhyada Boronic, oo ay ku jiraan Boc-phenylboronic acid, waxay si sahal ah u sameeyaan esters boronate marka ay la falgalaan nucleophiles, sida alkolada ama amines.Esters-yada boronate-ka ah ayaa markaa mari kara isbeddello kala duwan, oo ay ku jiraan falcelinta isku-xidhka Suzuki-Miyaura, isku xidhka Negishi, iyo isku xidhka Stille.Dareen-celintani waxay awood u siinaysaa samaynta unugyo dabiici ah oo isku dhafan oo leh qaabab beddelaadyo kala duwan iyo kooxo shaqeynaya.Boc-phenylboronic acid waxay si gaar ah faa'iido ugu leedahay soo bandhigidda unugyada phenylboronic acid molecules bartilmaameedka ah. Intaa waxaa dheer, boc-phenylboronic acid waxay door muhiim ah ka ciyaartaa kimisteriga daawada.Shaqada boronic acid waxay si xushmad leh ula falgeli kartaa diols ama kooxaha firfircoon ee boronate ester-xasaasiga ah ee bartilmaameedyada bayoolojiga, taas oo awood u siinaysa naqshadeeyayaasha enzyme-ku-salaysan boronate iyo ligands reseptor.Boc-phenylboronic acid waxaa lagu dari karaa inhibitors-molecule-yar-yar, peptides, ama dawooyinka soo saara si ay u bixiyaan guryaha la rabo ama kor loogu qaado bartilmaameedka gaarka ah.Xeryahooda boronate-ku-salaysan waxay muujiyeen ballan-qaadka daaweynta cudurrada kala duwan, oo ay ku jiraan kansarka, sonkorowga, iyo caabuqa. Soo koobid, 3-tert-Butoxycarbonylphenylboronic acid, ama Boc-phenylboronic acid, waxay helaysaa codsiyo kala duwan oo ku saabsan isku-darka organic iyo kiimikada daawada.Kooxdeeda BOC waxay u adeegtaa sidii koox ilaalin ah, taasoo u oggolaanaysa falcelinno door ah oo ku yaal meelaha kale ee molecule-ka.Intaa waxaa dheer, shaqeynta boronic acid waxay awood u siineysaa sameynta curaarta kaarboon-kaarboon, fududeynta isku dhafka maaddooyinka organic adag.Intaa waxaa dheer, boc-phenylboronic acid waxay door muhiim ah ka ciyaartaa kimistari daawaynta, halkaas oo loo isticmaalo qaabaynta boronate-ku-salaysan inhibitors enzyme iyo ligands reseptor.Guud ahaan, Boc-phenylboronic acid waa reagent qiimo leh oo gacan ka geysata horumarinta kiimikada synthetic iyo cilmi-baarista dawada.