Alaabta

(2S) -1-(Chloroacetyl) -2-pyrrolidinecarbonitrile waa xarun awood weyn u leh codsiyada kala duwan ee cilmi-baarista dawooyinka iyo isku-darka organic.Xaruntan, oo sidoo kale loo yaqaan (2S) -2-Chloroacetylpyrrolidine-1-carbonitrile, waxay leedahay sifooyin dhismeed gaar ah oo ka dhigaya mid qiimo leh horumarinta dawooyinka cusub iyo isku dhafka molecules organic adag. Hal codsi oo suurtagal ah (2S) -1- (Chloroacetyl) -2-pyrrolidinecarbonitrile waa adeegsigeeda sida dhismo dhisme ama dhexdhexaad ah oo ku saabsan isku-dhafka dabiiciga ah.Kooxdeeda firfircoon ee chloroacetyl iyo kooxda cyano (carbonitrile) waxay u oggolaanayaan soo bandhigida kooxo firfircoon oo dheeri ah iyo samaynta curaarta cusub ee kiimikada.Kala duwanaanshiyahani wuxuu ka dhigayaa mid faa'iido u leh isku-dhafka xeryahooda kala duwan, oo ay ku jiraan dawooyinka, agrochemicals, iyo kiimikooyinka khaaska ah.In goobta kiimikada daawada, (2S) -1- (Chloroacetyl) -2-pyrrolidinecarbonitrile ayaa loo sahamin karaa sida farmashiyaha suurtagalka ah ama qaab-dhismeed motif ee naqshadaynta daroogada.Qaab dhismeedka gaarka ah ee xarunta iyo kooxaha shaqeeya ayaa laga yaabaa in ay la falgalaan bartilmaameedyada bayooloji ee gaarka ah, sida ensaymes, reseptors, ama borotiinada, taas oo saameyn ku yeelanaysa hawlahooda.Iyadoo la bedelayo gobollada kala duwan ee molecule, cilmi-baarayaashu waxay baran karaan oo ay wanaajin karaan sifooyinkeeda farmasiga, taas oo keeni karta horumarinta wakiilada daweynta cusub. Intaa waxaa dheer, (2S) -1- (Chloroacetyl) -2-pyrrolidinecarbonitrile waxay u adeegi kartaa qalab qiimo leh oo kiimiko ah. cilmi baaris.Waxa loo isticmaali karaa in lagu calaamadiyo borotiinada bartilmaameedka ah ama molecules xiisaha leh, iyada oo siinaya hab lagu barto hab-dhaqankooda iyo isdhexgalka hababka noolaha.Marka lagu dhejiyo calaamado ama calaamado ku habboon xaruntan, cilmi-baarayaashu waxay la socon karaan qaybinteeda iyo qaababka isku-xirnaanta, iyagoo gacan ka geysanaya faham wanaagsan oo ku saabsan hababka noolaha. 2S) Magacaabista, waxay furaysaa fursadaha loogu isticmaalo isku-dhafka asymmetric.Xeryahooda Chiral waxay leeyihiin qaabab kala duwan oo atamka qaabdhismeedkooda, iyagoo siinaya suurtagalnimada abuuritaanka xeryahooda enantiopure, kuwaas oo ah unugyo ka jira mid ka mid ah laba nooc oo muraayad ah.Hantidan ayaa aad u qiimo badan marka la helo dawooyinka, maadaama dawooyinka enantiopure ay soo bandhigi karaan firfircoonida dawooyinka ee la xoojiyay iyo waxyeelooyinka soo raaca ee la yareeyey. isku duubni.Waxay awood u leedahay inay u adeegto sidii dhisme dhisme ah oo loogu talagalay isku-darka unugyo dabiici ah oo isku dhafan, oo ah barta bilawga horumarinta daroogada, iyo qalab loogu talagalay cilmi-baarista biochemical iyo bayooloji.Sahaminta dheeraadka ah iyo baadhista hantideeda ayaa balaadhi doonta fahamkayaga ku saabsan codsiyadeeda suurtagalka ah waxaana laga yaabaa inay horseeddo helitaanka dawooyinka cusub ee daweynta.