Alaabta

Xarunta (2R,3R,4R,5S,6S) -2- (acetoxymethyl) -6- (4-chloro-3- (4-ethoxybenzyl) phenyl) tetrahydro-2H-pyran-3,4,5-triyl triacetate waa molecule organic adag oo leh codsiyo suurtagal ah oo ku saabsan dhowr meelood oo kimistari iyo cilmi-baaris dawo ah. Mid ka mid ah isticmaalka suurtogalka ah ee xaruntan ayaa ku jira isku-dhafka organic.Joogitaanka kooxo badan oo shaqeynaya, oo ay ku jiraan acetoxymethyl, chloro, iyo ethoxybenzyl, waxay bixisaa habab kala duwan oo lagu maareeyo oo wax looga beddelo molecule-ka.Chemists waxay u isticmaali karaan xaruntan sidii walxo bilow ah si ay u abuuraan xeryahooda dabiiciga ah ee kakan, sida kuwa dhexdhexaadka ah ee dawooyinka ama soosaarayaasha alaabada dabiiciga ah.Iyagoo si istiraatiji ah u dooranaya oo wax ka beddelaya kooxo hawleed gaar ah, cilmi-baarayaashu waxay habayn karaan guryaha xarunta waxayna kor u qaadi karaan sifooyinka ay rabaan, sida dhaqdhaqaaqa noolaha ama milanka. Codsiga kale ee suurtagalka ah ee (2R,3R,4R,5S,6S) -2-(acetoxymethyl) 6- (4-chloro-3- (4-ethoxybenzyl) phenyl) tetrahydro-2H-pyran-3,4,5-triyl triacetate waxay ku jirtaa kimistariga daawada.Dhismaha xaruntu waxa uu ka kooban yahay dhawr astaamood oo caadi ahaan laga helo molecules-farmakooloji ahaan firfircoon, sida giraanta pyran iyo kooxda benzyl udgoon.Cilmi-baarayaasha dawooyinka ayaa sahamin kara awoodda dawooyinka ee xaruntan iyaga oo baranaya isdhexgalka ay la leeyihiin bartilmaameedyada noolaha, samaynta daraasaadka qaab-dhismeedka-shaqada, iyo qiimaynta waxtarkeeda daawaynta.Joogitaanka kooxda triacetate ayaa sidoo kale laga yaabaa inay bixiso faa'iidooyin dheeraad ah, sida xasilloonida la wanaajiyey, korodhka lipophilicity, ama kor u kaca xuubka, kuwaas oo ah sifooyinka wanaagsan ee horumarinta daroogada. Intaa waxaa dheer, stereochemistry gaar ah ee xarunta (2R,3R,4R,5S,6S) waxay gacan ka geysataa awooddeeda sidii dhisme chiral ee isku-dhafka asymmetric.Xarumaha chiral ee ku jira molecule-ku waxay siinayaan fursad loogu talagalay diyaarinta xeryahooda enantiomerically saafi ah, kuwaas oo muhiim u ah soo saarista daawooyinka iyo agrochemicals.Farmashiyeyaasha dabiiciga ah waxay u isticmaali karaan xaruntan sidii walxo bilawga ah ama waxay u soo bandhigi karaan dariiqa isku dhafan ee kakan si ay u helaan alaabooyin saafi ah oo firfircoon. Waxaa muhiim ah in la ogaado in la shaqaynta xaruntan ay u baahan tahay khibrad xagga maaraynta iyo soo saarista unugyada noole ee kakan.Cilmi-baadhayaashu waa inay qaataan taxaddarrada badbaadada ku habboon oo ay xaqiijiyaan nadiifinta xarunta iyo sifada ka hor inta aan la isticmaalin. phenyl) tetrahydro-2H-pyran-3,4,5-triyl triacetate waxay haysaa ballan sida xarun isku dhafan oo ku jirta isku dhafka dabiiciga ah, kimistariga daawada, iyo isku-dhafka asymmetric.Iyada oo leh kooxo badan oo shaqeynaya iyo stereochemistry gaar ah, waxay bixisaa fursado horumarinta xeryahooda cusub ee leh codsiyada suurtagalka ah ee qaybaha kala duwan ee sayniska, oo ay ku jiraan daahfurka daroogada, sayniska maadada, iyo bayoolajiga kiimikada.