Alaabta

Si loo baaro saameynta faa'iidada leh ee isku-dhafka butyrate, Lactobacillus casei, iyo L-carnitine ee qaabka colitis-ka.Afar kooxood ayaa helay butyrate afka, L-carnitine, Lactobacillus casei iyo isku darka saddex wakiil 10 maalmood oo isku xigta.Kooxaha soo haray waxaa ka mid ahaa kontaroolo taban iyo kuwo togan iyo koox been abuur ah.Makroscopic, baaritaannada histopathological, iyo biomarkers sida buro necrosis factor-alpha (TNF-α) iyo interlukin-1β (IL-1β), myeloperoxidase (MPO), thiobarbituric acid walxo fal-celin ah (TBARS), iyo ferric hoos u dhaca awoodda plasma (FRAP). ) ayaa lagu go'aamiyay xiidanka. Daaweynta isku-dhafka ah waxay muujisay saameyn faa'iido leh oo waxtar leh oo lagu yareeyo colitis marka la barbardhigo kantaroolka.Isbeddelka guud ee hoos u dhaca TNF-α (114.66 ± 18.26 vs 171.78 ± 9.48 pg / mg protein, P <0.05), IL-1β (24.9 ± 1.07 vs 33.06 ± 2.16 pg / mg borotiinka, P), <0.05. ± 0.03 vs 0.49 ± 0.04 μg/mg protein, P <0.01), MPO (15.32 ± 0.4 vs 27.24 ± 3.84 U/mg protein, P <0.05), iyo sare u qaadida FRAP (23.46 ± 5.2 ± 1.22 ± μl , P <0.05) waxay taageertaa doorbidida daaweynta isku dhafka ah marka la barbardhigo kontaroolada.Inkasta oo monotherapies ay sidoo kale waxtar u leedahay hagaajinta calaamadaha colitis, daawaynta isku dhafan ayaa aad uga fiicnaaday hagaajinta calaamadaha cadaadiska oksaydhka ee mindhicirka oo ay ku jiraan FRAP, TBARS, iyo MPO. Isku-dhafka hadda jira waa isku-dar ku habboon xakamaynta colitis tijaabo ah waana in lagu tijaabiyaa goobta caafimaad