Alaabta

2,3-Difluoro-4-ethoxybenzeneboronic acid waa iskudhis ka hela faa'iidooyin dhowr qeybood oo kimistari ah, gaar ahaan isku dhafka organic iyo kimistariga daawada.Iyada oo qaab-dhismeedkeeda gaarka ah iyo fal-celinta, waxay noqotay dhisme qiimo leh oo loogu talagalay abuurista molecules organic adag iyo xeryahooda dawooyinka.Mid ka mid ah codsiyada muhiimka ah ee 2,3-Difluoro-4-ethoxybenzeneboronic acid waxay ku jirtaa isticmaalka falcelinta isku-dhafka ah.Dareen-celinta isku-dhafka ah, sida isku-xidhka Suzuki-Miyaura iyo Buchwald-Hartwig, waa habab awood leh oo lagu dhisayo curaarta kaarboon-kaarboon iyo kaarboon-heteroatom.Dareen-celintan, 2,3-Difluoro-4-ethoxybenzeneboronic acid waxay u adeegi kartaa sidii qayb ester boronate ah, oo ka fal-celinaysa electrophiles kala duwan (tusaale, aryl halides, halides vinyl) oo hoos yimaada saamaynta kicinta ku habboon.Tani waxay awood u siinaysaa isku-dhafka xeryahooda kala duwan ee leh sifooyinka nafleyda firfircoon, sida wakiilada dawooyinka ama agrochemicals. Intaa waxaa dheer, joogitaanka atomyada fluorine ee 2,3-Difluoro-4-ethoxybenzeneboronic acid waxay siin kartaa hanti faa'iido leh oo ka soo baxa molecules.Beddelka fluorine wuxuu wanaajin karaa xasilloonida, lipophilicity, iyo astaanta farmashiyaha ee xeryahooda organic, taasoo ka dhigaysa musharaxiin waxtar badan leh.Sidaa darteed, isticmaalka istaraatiijiga ah ee 2,3-Difluoro-4-ethoxybenzeneboronic acid sida horudhac u ah isku-darka isku-dhafka daroogada-sida waxay ku siin kartaa helitaanka molecules fluorinated oo leh waxqabad bayooloji ah oo la wanaajiyey iyo sifooyinka physicochemical ee la jecel yahay. Intaa waxaa dheer, kooxda ethoxy ee ku jirta 2. ,3-Difluoro-4-ethoxybenzeneboronic acid waxay bixisaa kala duwanaansho dheeraad ah codsiyada synthetic.Waxaa lagu soo rogi karaa falcelinta beddelka nucleophilic, taas oo u oggolaanaysa soo bandhigida kooxo kala duwan oo shaqeynaya oo ku yaal booska ethoxy.Tani waxay awood u siinaysaa kala-soocidda xarunta si ay ugu habboonaato hantideeda ujeedooyin gaar ah ama inay soo bandhigto qodobbo dheeraad ah oo kala duwanaansho ah oo ku saabsan isku dhafka maktabadda si loo ogaado daroogada. kimistari daawo.Ka-qaybgalkeeda falcelinta isku-dhafan, isku-darka atamka fluorine, iyo derivatization ee booska ethoxy waxay ka dhigaysaa qalab qiimo leh oo loogu talagalay dhismaha xeryahooda dabiiciga ah ee kala duwan oo leh codsiyada dawooyinka suurtagalka ah.Adeegsigeedu waxa uu awood u yeeshaa isku xidhka molecules-ka adag iyo maktabadaha si loo helo dawooyinka waxana ay siisaa gelitaanka xeryahooda fluorinated oo leh hanti la hagaajiyay.