1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas: 41575-94-4
| Lambarka buugaagta | XD90684 |
| Magaca Alaabta | 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) |
| CAS | 41575-94-4 |
| Qaanuunka molecular | C6H12N2O4Pt |
| Miisaanka Molecular | 371.25 |
| Faahfaahinta Kaydinta | 2-8°C |
| Xeerka Tarifka La Iswaafajiyay | 28439090 |
Tilmaamaha Alaabta
| Muuqashada | Caddaan ilaa budo caddaan ah |
| Qiimayn | 99% |
| Biyo | ≤0.5% |
| Khasaare xagga qallajinta | ≤0.5% |
| Chlorides | ≤100pm |
| Walxaha laxidhiidha | ≤0.25% |
| Najaasad kasta oo aan la cayimin | ≤ 0.1% |
| Dhammaan wasakhda kale | ≤0.5% |
| 1,1-Cyclobutanedicarboxylic acid | ≤ 0.5% |
Jiilka labaad ee platinum adag dawooyinka antineoplastic.Dhaqdhaqaaqa antitumor spectrum iyo antitumor waxay la mid yihiin kuwa cisplatin, laakiin milanka biyaha ayaa ka fiican kan cisplatin, iyo sunta kelyaha ayaa sidoo kale hooseysa.Waxay saameyn wanaagsan ku leedahay daaweynta kansarka sanbabada unugyada yaryar, kansarka ugxansidaha, madaxa iyo qoorta squamous cell carcinoma, burada xiniinyaha, lymphoma malignant, iwm. Waxa kale oo loo isticmaali karaa kansarka ilmo-galeenka, kansarka kaadiheysta, iwm.
Jiilka labaad ee dawooyinka kansarka ka hortagga platinum ayaa asal ahaan leh shaqooyin isku mid ah waxayna isticmaalaan cisplatin.Way ka firfircoon tahay cisplatin ee burooyinka qaarkood, wayna ka xoog badan tahay cisplatin sida radiosensitizer hoos yimaada xaaladaha hypoxic.Inta badan loo isticmaalo kansarka ugxan-sidaha, kansarka xiniinyaha, kansarka sambabada unugyada yaryar iyo kansarka madaxa iyo qoorta.
Carboplatin waa dawada platinum-ku-saleysan ka-hortagga kansarka kaas oo waxyeello u geysta DNA-ga iyadoo sameysa isku xirka intrachain ee haraaga guanine ee ku xiga.Saamaynta antitumor ee daawooyinkan waxaa lagu gaaraa luminta hagaajinta DNA-da ee aan dheeli tirnayn (MMR) dhaqdhaqaaqa iyo kicinta dhimashada unugyada ee barnaamijka.
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