Alaabta

1-Methyl-4-pyrazole boronic acid pinacol ester waa xarun leh codsiyo badan oo kala duwan, gaar ahaan goobta isku dhafka dabiiciga ah.Qaab-dhismeedkeeda gaarka ah iyo fal-celinta waxay ka dhigaysaa mid qiimo leh fal-celin kiimikaad oo kala duwan iyo sidii dhisme loogu talagalay isku-dhafka molecules-kakan curaarta kaarboon-heteroatom.Kooxda boronic acid ee ku jirta molecule waxay mari kartaa falcelinta isku-xidhka Suzuki-Miyaura, taas oo awood u siinaysa ku-xidhnaanta unugyada 1-methyl-4-pyrazole ee xeryahooda kale ama kooxaha shaqeeya.Dareen-celintani waxay u oggolaanaysaa farmashiyeyaashu inay abuuraan xeryahooda dabiiciga ah ee isku dhafan oo leh qaab-dhismeedyo iyo sifooyin isku dhafan. Intaa waxaa dheer, kooxda pinacol ester ee molecule waxay bixisaa xasillooni waxayna ilaalisaa shaqeynta boronic acid inta lagu jiro falcelinno kala duwan.Kooxdan ilaalinta si fudud ayaa looga saari karaa xaalado khafiif ah, si ay u soo bandhigaan kooxda boronic acid isbeddello dheeraad ah.Sidaa darteed, 1-Methyl-4-pyrazole boronic acid pinacol ester waxay u adeegtaa sidii dhexdhexaadiye dhexdhexaad ah oo ku saabsan isku dhafka daawooyinka, agrochemicals, iyo kiimikooyinka kale ee wanaagsan. musharaxiinta daroogada.Adigoo isticmaalaya 1-Methyl-4-pyrazole boronic acid pinacol ester wax bilow ah, farmashiyeyaashu waxay soo bandhigi karaan unugyada 1-methyl-4-pyrazole molecule bartilmaameedka ah, iyagoo siinaya astaamo gaar ah ama hawlqabadyo.Iskudhisyada ka soo baxa ayaa laga yaabaa inay soo bandhigaan dhaqdhaqaaqa bayooloji ee la xoojiyay, farmashiyaha la hagaajiyay, ama sunta oo yaraatay. Intaa waxaa dheer, 1-Methyl-4-pyrazole boronic acid pinacol ester waxay qiimo u leedahay sayniska maadada iyo catalysis.Waxay u adeegi kartaa sida ligand, isku-dubbaridka biraha birta ah iyo ka-qaybgalka fal-celinta catalytic ee kala duwan.Kooxda boronic acid ee xaruntan waxay samayn kartaa dhismo leh biraha kala-guurka, taas oo u oggolaanaysa firfircoonida curaarta CH ama kicinta falcelinta isku-xidhka ah.Guryahaani waxay ka dhigayaan mid faa'iido u leh isku-darka walxaha shaqeynaya ama horumarinta hababka cusub ee catalytic. Soo koobid, 1-Methyl-4-pyrazole boronic acid pinacol ester waa xarun isku dhafan oo leh codsiyo muhiim ah oo ku saabsan isku-darka organic, daawooyinka, sayniska alaabta, iyo catalysis.Shaqadeeda boronic acid iyo kooxda ester pinacol waxay ka dhigtaa mid faa'iido u leh kaarboon-kaarbon ama kaarboon-heteroatom dammaanadda falcelinta samaynta, taasoo awood u siinaysa dhismaha molecules adag.Codsiyadeedu waxay ku baahsan yihiin warshado kala duwan, oo ay ku jiraan isku-darka dawooyinka, horumarinta agabka shaqaynaya, iyo horumarinta nidaamyada catalytic.Kala-duwanaanta iyo falcelinta 1-Methyl-4-pyrazole boronic acid pinacol ester waxay ka dhigtaa qalab qiimo leh oo loogu talagalay farmashiyeyaasha ka shaqeeya isku-darka xeryahooda cusub iyo naqshadeynta xalalka cusub.