Alaabta

1- (2,3-Xylyl)piperazine monohydrochloride, oo sidoo kale loo yaqaan 2,3-dimethoxyphenylpiperazine hydrochloride, waa xarun kiimiko ah oo leh codsiyo kala duwan oo ku saabsan cilmi-baarista dawooyinka iyo horumarinta.Xaruntan waxaa inta badan loo isticmaalaa sidii dhexdhexaad ah ee isku-dhafka molecules bioactive ee kala duwan. Mid ka mid ah isticmaalka ugu weyn ee 1- (2,3-Xylyl) piperazine monohydrochloride waa doorka ay ku leedahay dhismaha molecules ee lagu beegsanayo habka dhexe ee neerfayaasha.Iyadoo lagu darayo 2,3-dimethoxyphenylpiperazine moiety ee molecules daroogada, cilmi-baarayaashu waxay wax ka beddeli karaan qaab-dhismeedkooda kiimikaad, kor u qaadida sifooyinka dawooyinka iyo hagaajinta xiriirkooda iyo xulashada soo-dhoweynta gaarka ah. Intaa waxaa dheer, 1- (2,3-Xylyl)piperazine monohydrochloride ayaa la helay. si ay u lahaadaan xidhiidhka soo-dhoweeyayaasha neuronal ee kala duwan, oo ay ku jiraan serotonin iyo dopamine reseptors.Hantidani waxa ay kicisay xiisaha isticmaalka suurtagalka ah ee qalab si ay wax u bartaan oo ay u fahmaan xanuunada neerfaha kala duwan iyo xaaladaha dhimirka.Iyadoo la baarayo isdhexgalka xaruntan oo leh reseptors, cilmi-baarayaashu waxay heli karaan fikrado qiimo leh oo ku saabsan hababka asaasiga ah ee xaaladahan, kuwaas oo gacan ka geysan kara horumarinta waxqabadyo daaweyneed oo cusub. Cilmi-baaris ayaa sidoo kale muujisay in 1- (2,3-Xylyl) piperazine monohydrochloride Waxay muujisaa firfircoonida ka hortagga bakteeriyada iyo fungi qaarkood.Awooddani waxay keentay sahaminta iyada oo ah horudhac suurtagal ah horumarinta wakiilada antimicrobial.Iyadoo wax laga beddelayo qaab-dhismeedkeeda ama lagu daro unugyo kale, cilmi-baarayaashu waxay abuuri karaan dawooyin awood leh oo waxtar leh oo loogu talagalay daaweynta caabuqyada microbial. Waxaa muhiim ah in la ogaado in 1- (2,3-Xylyl) piperazine monohydrochloride waa in si taxadar leh loo maareeyo iyadoo la raacayo hab-maamuuska badbaadada saxda ah.Aqoonta xaashida xogta badbaadada iyo ka faa'iidaysiga qalabka ilaalinta ku haboon ayaa lama huraan u ah si loo hubiyo in si badbaado leh loo maamulo loona yareeyo khatar kasta oo la xidhiidha xaruntan. cilmi baarista dawooyinka.Isticmaalkeeda sida dhexdhexaadka ah ee isku-darka daroogada ayaa u oggolaanaysa horumarinta molecules oo leh codsiyada daweynta ee suurtogalka ah ee habka dhexe ee dareenka.Intaa waxaa dheer, xiriirka ay u leedahay dareemayaasha dareemayaasha iyo guryaha antimicrobial ayaa ka dhigaya qalab qiimo leh oo lagu barto cudurrada neerfaha iyo cudurrada faafa.Si kastaba ha ahaatee, waa in taxadar la sameeyaa marka la shaqaynayo xaruntan si loo xaqiijiyo badbaadada loona yareeyo khataraha iman kara.